丙泊酚和异氟烷对老年病人全麻术后认知功能影响的比较医学.docVIP

丙泊酚和异氟烷对老年病人全麻术后认知功能影响的比较医学 目录 TOC \o 1-9 \h \z \u 目录 1 正文 1 文1：丙泊酚和异氟烷对老年病人全麻术后认知功能影响的比较医学 1 1 对象与方法 3 2 结果 4 文2：关于高龄患者全麻术后认知功能障碍的观察与护理 8 1临床资料 8 参考文摘引言： 10 原创性声明（模板） 12 文章致谢（模板） 12 正文 丙泊酚和异氟烷对老年病人全麻术后认知功能影响的比较医学 文1：丙泊酚和异氟烷对老年病人全麻术后认知功能影响的比较医学 Comparison of the Cognitive function of the influence in elder patients with propofol and isoflurance after general anesthesia 【Abstract】 Objective To investigate the influence of propofol and isoflurane on the cognitive function in elderly 30 ASAⅠ～Ⅱpatients，scheduled for elective abdominal surgery in the HospitalAffiliated to the Medical College of Qingdao Univeitywere the patients have no cardiac or neuropsychiatric diseases or history of taking corresponding patients were divided into propofol （P group） and isoflurane subgroups （I group）（n=15 in each subgroup）.Anesthesia was induced with intravenous propofol ~/kg，fentanyl 3~4μg/kg，vecuronium /kg，and maintained with intravenous propofol 100~150μg/（kg·min）or isoflurane inhalation （1%~2%） modulated by hemodynamic paramete （MAP、HR、SPO2） were recorded before surgery and at the time of 1h、4h、24h、48h after state examination was performed before anesthesia and 1h、4h、24h、48h after volume of liquid and blood received and lost during the operation were also All the 30 patients were involved in the analysis of were no significant differences between the two groups in age、height、weight and sex difference in the hemodynamic paramete （MAP、HR、SPO2） in the same perioperative period of the volume of liquid and bloodthat patients lost and received during the operation was found when compared between all patients，the MMSE scores at 1h after operation were significantly lower than the baseline value （P＜）.The MMSE scores at 4h after operation in I group patients were significantly longer than that inP group （P＜）.There were no significant differences between the MMSE scores at 24 or 48h after operation of the baseline value（P＞）.Conclusion Both propofol and