出生缺陷高发区地球化学环境中微量元素分析.docVIP

出生缺陷高发区地球化学环境中微量元素分析 目录 TOC \o 1-9 \h \z \u 目录 1 正文 1 文1：出生缺陷高发区地球化学环境中微量元素分析 1 1 资料与方法 3 2 结果 4 3 讨论 5 文2：矮小儿童血清微量元素分析 6 1 对象与方法 6 1．1 一般资料 6 2 结果 7 3 讨论 7 参考文摘引言： 8 原创性声明（模板） 9 文章致谢（模板） 10 正文 出生缺陷高发区地球化学环境中微量元素分析 文1：出生缺陷高发区地球化学环境中微量元素分析 Analysis on trace element of geochemical environment in high prevalence area of birth defects Abstract： Objective To explore the relatiohip between the content of trace elements of geochemical environment and the incidence of birth defects in the high prevalence area of birth The concentration of 14 kinds elements in the samples of soil,corn,water and hair from the high prevalence areas and the low one in Shanxi province were meurated with Inductively Couplled Plasma(IGP) machine in the the data were statistically analyzed and compared to find the difference of geochemical environment among these Compared with the samples from the low prevalence area,the concentration of sulfur in the natural environment samples from high prevalence areas was significantly higher,but the concentration of strontium and aluminum were ,and there were significant difference between the concentration of Mg,Mn,Mo,Fe,Cu,Ca and Sn in water and corn from the high prevalence birth defects area and that from the low The concentration of trace elements in the samples of soil,corn,water and hair from the high birh defects ratio area and the low one has great difference,which can be used to deduce the occurrence of birth defects. Key words：high prevalence area;incidence;concentration of elements;birth defects 出生缺陷发生与环境因素异常有关已被证实〔1〕，但已往的相关研究更多关注的是污染环境、生活环境及工作环境等次生环境的影响作用〔2-5〕。而大量研究表明，出生缺陷发生具有一定的地域集中性，存在明显的高发地区〔6,7〕。探讨出生缺陷高发区 自然 环境的异常特征，对出生缺陷的预防和干预很有意义。山西省是我国出生缺陷高发区，1996～2002年的调查数据表明，全省平均出生缺陷发生率为177%， 农村 地区高达277%〔8〕。本文采用对照比较法，探索出生缺陷发生率与地球化学环境异常特征之间的相关关系，为有效干预和防治出生缺陷的发生提供 科学 依据。 1 资料与方法 11 样品采集 选择出生缺陷高发的山西省交口县和中阳县作为研究区，出生缺陷发生率低的平遥县作为对照区。根据流行病学调查结果，在出生缺陷高发区，选择19个自然村落，分别采集表层土壤(耕地和林地共146份样本)、饮用水(井水和河水共248份)、粮食(玉米共170份)和人体头发