血脂异常对中老年人脑梗死的影响.docVIP

血脂异常对中老年人脑梗死的影响 目录 TOC \o 1-9 \h \z \u 目录 1 正文 1 文1：血脂异常对中老年人脑梗死的影响 1 1 资料与方法 3 1. 1 病例选择 3 2 结果 4 3 讨论 4 文2：血脂异常对急性心肌梗死静脉溶栓疗效的影响 6 1　　资料与方法 7 2　　结果 8 3　　讨论 8 参考文摘引言： 9 原创性声明（模板） 10 文章致谢（模板） 10 正文 血脂异常对中老年人脑梗死的影响 文1：血脂异常对中老年人脑梗死的影响 【Abstract】 Objective To investigate the effect of anomal-blood fat level on cerebral infarction in aged peo. Methods Screening 100 patients with cerebral infarction, aged 45～81. Contrasted to 100 health volunteer, collected 3 ml venous blood from subjects in the early morning, separated the serum after centrifugalization, and then put the serum in refrigerator, set up the temperature at -25 ℃. Detected the lipoprotein（a）level by using double anti-sandwich ELISA, detected the total cholesterol and triglyceride content by oxidation enzyme methord, detected the high-deity lipoprotei content by using magnesium phosphotungstic acid sedimentation, and calculated the low-deity lipoprotein by the formula LDL-C=TC-（TG/+HDL-C）, detected apolipoprotein A and apolipoprotein B by immunoturbidimetry. Resuts The level of lipoprotein（a）; total cholesterol; triglyceride;. low-deity lipoprotein and apolipoprotein B in serum of cerebral infarction patients were higher than control group, and compared with control, the abnormality incidence rate of lipids concentration had significant difference, P. Conclusion There was close relatiohip between abnomal-blood fat level and cerebral infarction in aged patients，and regulation the level of blood fat has important significance on preventing and curing cerebral infarction in aged patients. 【Key words】 blood fat；cerebral infarction；lipoprotein；total cholesterol；triglyceride 脑梗死是神经内科最常见的疾病之一,发病率高、致残率高。随着社会的进步和饮食结构的改变,在我国中老年人群中急性脑梗死呈逐年上升的趋势,调查结果显示近10 年来发病率明显增高。脑梗死是指脑部的动脉粥样硬化, 使动脉管腔狭窄、闭塞, 导致急性脑供血不足或脑动脉血栓形成, 造成局部脑组织坏死。而动脉硬化性脑梗死是脑梗死最常见的原因, 约占所有脑梗死的70 %左右, 常见的诱因有高血压、高血脂、糖尿病等［1］ 。目前, 高血压作为脑梗死极其重要的危险因已被医学界所认可［2］。多数学者认为高血脂也是脑梗死发生的危险因素之一，但是由于研究较少，本文通过检测脑梗死患者血清中脂蛋白a（LPa）、血清总胆固醇（TC） 、甘油