穴位埋线联合盐酸二甲双胍片治疗肾虚痰湿型多囊卵巢综合征胰岛素抵抗50例临床观察(1).pdfVIP

穴位埋线联合盐酸二甲双胍片治疗肾虚痰湿型多囊卵巢综合征 胰岛素抵抗50例临床观察 蒋雪霞;孟君 【摘要】Objective To observe the effect of acupoint catgut implantation combined with metformin hydro -chloride tablets on renal deficiency and phlegm -damp type polycystic ovarian syndrome ( PCOS) with insulin resist-ance ( IR) .Methods 100 PCOS patients were randomly divided into two groups .50 patients in control group were treated by metformin hydrochloride tablets .50 cases in treatment group were treated by acupoint catgut implantation in the non-menstrual period on the basis of control group treatment .The changes of BMI, FPG, 2 hPG, fasting insulin, postprandial 2h insulin, Homeostasis model of insulin resistance index (HOMA-IR), HOMA-β, T, TG, HDLC,nbsp;LDL-C, ApoA, APOB,LH, FSH, E2 , T and LH/FSH levels were observed and compared in two groups .Results The levels of BMI after treatment were decreased signif-icantly in two groups (P 0.05), there was difference between groups (P0.05).The levels of FPG, fasting insulin, 2 hPG, postprandial 2 h insulin, HOMA-IR and HOMA-βafter treatment were obviously decreased in treatment group (P0.05), but the levels of FPG, fasting insulin, HOMA-IR and HOMA-βafter treatment were decreased in control group (P0.05).And there were significant differences between two groups on the levels of FPG, fasting insulin and HOMA-IR after treatment (P0.05).The levels of TG, LDL-C and Apo-A after treat-ment were decreased and the level of HDL -C was increased in treatment group (P0.05).But in control group the levels of TG and LDL -C were reduced and the level of HDL -C was increased after treatment ( P0.05 ) .And there were significant differences between two groups on the changes of levels of TG , LDL-C, HDL-C and Apo-A after treatment (P0.05).The levels of LH, LH/FSH and T after treatment were significantly decreased in treat-ment group (P0.05).But in control group the levels of LH and T were significantly reduced after treatment (P0.05).