妊娠期糖尿病的规范化治疗对妊娠结局的影响.docVIP

GIP Chinese General Practice 2012年9月第15卷第98期 ·3009 · · 论 著 · 妊娠期糖尿病的规范化治疗对妊娠结局的影响 李琦，马彦彦 【摘要】 目的 探讨妊娠期糖尿病 (GDM) 规范化治疗对妊娠结局的影响。方法 选择我院101例GDM 孕妇， 根据血糖控制情况分为血糖控制满意组(满意组78例)和血糖控制不满意组(不满意组，23例),与同期住院分娩的 无内科合并症的糖代谢正常孕妇(正常对照组，80例)进行对比，分析在孕妇和围生儿并发症发生率方面有无差异。 结果 满意组孕妇妊娠期高血压疾病、羊水过多、早产、胎膜早破及产后出血发生率和围生儿巨大儿、胎儿窘迫、新 生儿窒息及高胆红素血症发生率与正常对照组比较，差异均无统计学意义 (P0.05); 不满意组的妊娠期高血压疾 病、羊水过多、早产、胎膜早破、产后出血、巨大儿、胎儿窘迫、新生儿窒息及高胆红素血症发生率均高于满意组 (P0.05)。 结论 GDM 如能得到满意控制，孕妇和围生儿并发症发生率均可降低到糖代谢正常孕妇的水平，加强孕 期管理，规范化治疗GDM, 能有效控制血糖，降低母婴并发症的发生率。 【关键词】 糖尿病，妊娠；规范化治疗；妊娠结局 【中图分类号】 R714.256 【文献标识码】 A 【文章编号】1007-9572(2012)09-3009-03 The Effect of Standardized Treatment of Gestational Diabetes Mellitus on Pregnancy Outcome LI Qi, Ma Yan -yan. Yuquan Hospital of Tsinghua University,Beijing 100049,China 【Abstract 】 Objective To study the effect of standardized treatment of gestational diabetes mellitus(GDM) on preg- nancy outcome. Methods Totally 101 pregnant women with GDM were divided into satisfactorily controlled group(satisfactory group,n=78)and unsatisfactorily controlled group(unsatisfactory group,n =23) according to the level of serum glucose. The maternal and perinatal complications were compared between subjects with normal tolerance and without medical complications (control group,n=80). Results The maternal and perinatal complications were not significantly different between satisfactory group and control group(P0.05). The incidences of pregnancy -induced hypertension, polyhydramnios,preterm delivery, premature rupture of membranes, postpartum hemorrhage, fetal macrosmia, fetal distress, neonatal asphyxia, and hyperbiliru- binemia were significantly higher in the unsatisfactory group than in the satisfactory group(P0.05). Conclusion Proper per- inatal management and standardized GDM treatment are important to control the level of serum glucose and decrease the maternal and perinatal c