肺结核（英文版）.pptVIP

Pulmonary tuberculosis (PTB) EtiologyMycobacterium tuberculosis Transitions in Childhood Tuberculosis Not infected (50-70%) Infected (30-50%) Diseased (10-30%)Within 2 years (50%) Lifelong (50%)Latent TB (70-90%)Never develop active disease(90%) Contact with smear positive index case Common clinical types of pulmonary TB in childrenPulmonary TBTB of trachebronchial lymphnodesPrimary complexAcute miliary TB of the lungs Primary pulmonary TBThe main types of pulmonary TB in children 1. Primary complex：mostly seen in younger childrenBacilli multiplies and spread via lymphatics causing lymphadenopathyPrimary complex: dumbbell shape lesions lung lesion, lymphangitis and lymphadenopathy Radiographs could show lung parenchymal disease, lymph node enlargement 1. Primary complexDumbbell shape lesions： Lung lesion, Lymphangitis, Lymphadenopathy 1. Primary complexDumbbell shape lesions： Lung lesion, Lymphangitis, Lymphadenopathy Enlargement of lung lymph nodes and mediastinal lymph nodesCan cause compression2. TB of trachebronchial lymphnodes 2. TB of trachebronchial lymphnodesEnlargement of lung lymph nodes and mediastinal lymph nodes 2. TB of trachebronchial lymphnodes A consequence of primary or post primary disease(3-6ms later)Hematogenous disseminationNodules measuring 2-3 mm in diameterMore in lower lung zones Perhaps the only radiographic finding that maybe highly suggestive of tuberculosis in infants and children Easy to concurrent tuberculosis meningitis3. Acute miliary TB of the lungs 3. Acute miliary TB of the lungsMillet sample nodules 3. Acute miliary TB of the lungsMillet sample nodules TB toxemiaRespiratory symptomssymptoms(various)low heat, fatigue, anorexia, night sweats, angularCough, expectoration, hemoptysis, chest pain, breathing difficultiesClinical manifestationsLung signs is not obviouslung raleSlow onset Hi