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Obefazimod(Standard)

Cat.No.:HY-100870R

CASNo.:1258453-75-6

分⼦式:C₁₆H₁₀ClF₃N₂O

分⼦量:338.71

作⽤靶点:HIV;ReferenceStandards

作⽤通路:Anti-infection;Others

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性Obefazimod(Standard)是Obefazimod(HY-100870)的分析标准品。本产品⽤于研究及分析应⽤。

Obefazimod(ABX464)是⼀种有效的抗HIV剂。Obefazimod作⽤于受刺激的外周⾎单个核细胞(PBMCs)，抑

制HIV-1复制，IC50为0.1μM⾄0.5μM。

IC50TargetIC50:0.1-0.5μM(HIV-1,inPBMCs)[1]

REFERENCES

[1].CamposN,etal.LonglastingcontrolofviralreboundwithanewdrugABX464targetingRev-mediatedviralRNAbiogenesis.

Retrovirology.2015Apr9;12:30.

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Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

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