电针足三里对糖尿病兔胃电信号及压力的影响.pdfVIP

摘要 目的 研究电针足三里对糖尿病兔胃电信号及压力的影响 实验设计及方法 将 60 只新西兰兔随机分为 DM 组（四氧嘧啶造模）及 C 组。6 周后，将存活 者再分别随机分成DM1组和C1组（非穴位），DM2组和C2组（足三里）。实验兔胃内注入生理 盐水 200ml，固定电针疏密波，频率 20 次/分，电压 22V，电流 1mA，比较四组兔电针前后胃 电信号、压力及DM、C组兔胃壁光镜变化。 结果 ①电针前，DM组胃电信号（DM1 0.35±0.07mv；DM2 0.38±0.08mv）和压力（DM1 17.60 ±1.26mmHg；DM2 18.29±1.06mmHg）明显低于C 组胃电信号（C1 0.52±0.10mv；C2 0.49± 0.08mv）和压力（C1 20.39±1.10mmHg；C2 21.05±1.38mmHg）(P 0.05)。②电针足三里后 胃电信号增强（DM2 0.50±0.07mv；C2 1.01±0.15mv），压力升高（DM2 21.58±1.25 mmHg； C2 25.70±1.55mmHg），与电针非穴位后胃电信号（DM1 0.38±0.07mv；C1 0.55±0.10mv） 及压力（DM1 17.36±1.24mmHg；C1 20.22±1.11mmHg）比较差异有统计学意义(P 0.05)。 ③胃压力随着胃电信号的增强而增大，两者呈直线相关关系。④ DM组兔胃壁平滑肌肌束间水 肿疏松，结缔组织增生，淋巴细胞浸润。 结论 DM 兔胃电信号和胃压力比正常兔小，其胃壁可能出现类似炎症病理改变；电针足三里可 使其胃电信号增强和胃内压力升高；电针足三里可能可改善糖尿病胃收缩力。 关键词 糖尿病兔；电针；足三里；胃电信号；胃压力 I    ABSTRACT OBJECTIVE To study the effects of electroacupuncture at the Zusanli point on gastric electrical signal and pressure in diabetic rabbits. MATERIALS AND METHODS Forty New Zealand rabbits were rendered diabetic with an i.v. injection of alloxan(DM group) and twenty were normal control(C group). After 6 weeks, the survived rabbits were divided into four groups, DM1 group and C1 group were accepted electroacupuncture at non-acupuncture points, DM2 group and C2 group were accepted electroacupuncture at the Zusanli points. 200ml isotonic Na chloride was respectively injected into each rabbit’s stomach. The gastric electrical signal and pressure in the four groups were recorded and evaluated in different time of electroacupuncture, using electroacupuncture apparatus with distant-dense wave, a frequency of 20c.p.m. and voltage of 22V, electric current of 1mA. The differences of stomach wall in DM groups and C groups were observed with a microscope. RESULTS ① There were significant differences