阿奇霉素治疗成人支原体肺炎23例临床效果分析.docVIP

阿奇霉素治疗成人支原体肺炎23例临床效果分析 　　[摘要] 目的 探讨分析阿奇霉素治疗成人支原体肺炎的临床效果。方法 选取我院收治的支原体肺炎成人患者46例，随机均分为对照组和观察组，对照组使用红霉素治疗，观察组使用阿奇霉素治疗。比较两组患者治疗后的临床症状消失时间，胸片恢复正常时间，住院时间，治疗总有效率及不良反应发生率的差异。结果 观察组患者临床症状消失时间、胸片恢复正常时间及住院时间均明显低于对照组，两组比较差异有统计学意义（P0.05）；观察组治疗总有效率为95.7%，明显高于对照组的65.2%（P0.05）。观察组不良反应发生率为13.0%，明显低于对照组的47.8%（P0.05）。结论 阿奇霉素治疗成年支原体肺炎疗效显著，能缩短住院时间，减少不良反应发生。 　　[关键词] 阿奇霉素；红霉素；支原体肺炎 　　[中图分类号] R563.1 [文献标识码] B [文章编号] 2095-0616（2013）24-72-02 　　Analysis on clinical efficacy of azithromycin for the treatment of 23 adult mycoplasmal pneumonia patients 　　CHEN Changbiao 　　Department of Respiratory Medicine，the Peoples Hospital of Hannan District，Wuhan 430090，China 　　[Abstract] Objective To investigate clinical efficacy of azithromycin for the treatment of adult mycoplasmal pneumonia patients. Methods 46 cases of mycoplasmal pneumonia in our hospital were randomly divided into control group and observation group.Control group were treated with erythromycin.Observation group were treated with azithromycin.The clinical symptoms disappeared time，chest X-ray recovery time，hospital stay，total effective rate and adverse reactions rate of two groups were compared. Results The clinical symptoms disappeared time，chest X-ray recovery time，hospital stay of observation group were significantly lower than control group（P0.05）.The total effective rate of observation group（95.7%） was significantly higher than control group（65.2%），P0.05.The adverse reactions rate of observation group was significantly lower than control group（P0.05）. Conclusion Azithromycin for the treatment of mycoplasmal pneumonia can ensure curative effect，reduce hospital stay and adverse reactions rate. 　　[Key words] Azithromycin；Erythromycin；Mycoplasma pneumonia 　　支原体肺炎是一种多由支原体感染所致的常见的社区获得性非典型肺炎，而且该病的发病率逐年上升[1]。大环内酯类药物如阿奇霉素、红霉素等是该病的主要治疗药物[2]。本研究以我院收治的46例支原体肺炎成年患者为研究对象，旨在探讨分析阿奇霉素治疗成人支原体肺炎的临床效果，现将研究结果报道如下。 　　1 资料与方法 　　1.1 一般资料 　　选取我院2011年10月～2013年6月期间收治的46例支原体肺炎成人患者作为研究对象，所有患者症状均符合支原体肺炎确诊标准[3]：阵发性干咳，呼吸道症状明显；头孢类抗生素或青霉素治疗无效；早期胸部X线以肺间