Similarity of fMRI Activity Patterns in Left Perirhinal外文翻译.pdfVIP

The Journal of Neuroscience, November 20, 2013 • 33(47):18597–18607 • 18597 Behavioral/Cognitive Similarity of fMRI Activity Patterns in Left Perirhinal Cortex Reflects Semantic Similarity between Words 1,2 1 3 4 4 1,2 Rose Bruffaerts, Patrick Dupont, Ronald Peeters, Simon De Deyne, Gerrit Storms, and Rik Vandenberghe 1 2 3 Laboratory for Cognitive Neurology, Department of Neurosciences, Neurology Department, and Radiology Department, University Hospitals Leuven, 3000 Leuven, Belgium, and 4Laboratory of Experimental Psychology, Humanities and Social Sciences Group, University of Leuven, 3000 Leuven, Belgium How verbal and nonverbal visuoperceptual input connects to semantic knowledge is a core question in visual and cognitive neuroscience, withsignificantclinicalramifications.Inan event-relatedfunctionalmagneticresonanceimaging(fMRI)experimentwedeterminedhow cosine similarity between fMRI response patterns to concrete words and pictures reflects semantic clustering and semantic distances between the represented entities within a single category. Semantic clustering and semantic distances between 24 animate entities were derived from a concept-feature matrix based on feature generation by 1000 subjects. In the main fMRI study, 19 human subjects performed a property verification task with written words and pictures and a low-level control task. The univariate contrast between the semantic and the control task yielded extensive bilateral occipitotemporal activation from posterior cingulate to anteromedial temporal cortex. Entities belonging to a same semantic cluster elicit