益肾降压方对老年高血压血管内皮功能调节作用及机理研究.pdfVIP

同时升 高 NO 、PG工2、CGRP 水平有关 。 关键词 益 肾降压方 ; 老年 高血压 ; 血管 内皮功能 R eg u la tio n a n d m ech a n ism o n .v a scu la r en d o th e lia l fu n etio n in elderly h yP erten sion by Y ish enj iangya P reseriP tion S P eeia lity : M ed iealD eP artm en t O f T C M A u th o r : Z h ao L iq u n Tu to r : G u o W 亡ix in g A b str a C t o bjeetive: Y ishenjiangya PreseriPtion effe ets elderly esseniial hyPertension and b]ood liP ids (serum total cholesterol，triglyeerides，low den sity liPop rotein eholesterol， h igh den sity lipoprotein eholesterol)，endothelin 一l (E T 一l ) and nitric ox ide (N O )， throm boxane B Z (T X B Z) and Prostaeyelin (PG IZ)，angioten sin 11 (An g 11 ) and ealeiton in gene一related P ePtide (C G RP ) and to exP lore their elderly hyPerten sive vaseu lar regu latio n o f en d o the lia l fun etio n an d m eeh an ism . M eth o d : 1. S eleet 2 00 6 一2 0 0 7 ，S h an d on g M ed ieal U n iv ersity A ffi liated H o sP ita l o f 5 6 ca se s o r P atients to m e et d ia gn o stie eriteria for W e stern e ld erly P atients w ith h y P erten sio n an d k id n ey q i d efie ien ey sy n d ro m e T C M sy n dro m e d iffe rentiatio n criteria ， a ll se lected P atien ts we re ran d om ly d iv id ed in to tw o gro uP s，co n trol g ro u P ，ex P erim en ta l g ro u P an d eonrt o l grouP rece iv ed o ral eaP to P ril，ex P erim enia l gro uP w ere treated o n the basis of Y ishenjiangya PreseriPtion service，treatm ent for 4 w eek s，b lood Pressure ehanges b efore and aft er treatm ent，C h inese m edicine symP tom efficaey ，an d b lood liP ids (serum totaleholesterol，4)，endothelin 一1 (E T 一1) and n itrie ox ide (N O )，thr om boxane