《Online coupling of “Dip-it” polymer monolith》.ppt

Online coupling of “Dip-it” polymer monolith microextraction with plasma assisted laser desorption ionization mass spectrometry 2016.01.21 Liuwei Polymer monolith has been considered as an attractive material for sample pretreatment, because of its advantages such as easy preparation, high permeability, satisfactory loading capacity, large surface area and good control of porosity. The extraction device used a Dip-it sampler coated with a MWNT incorporated monolith, and the analytes adsorbed on monoliths were effectively desorbed by laser, improving detection sensitivity. A polymer monolith was prepared on the external surface of the glass capillary of the Dip-it sampler; the monolith coated sampler was then applied for microextraction. A multi-wall carbon nanotube (MWNT) incorporated monolith was used in this experiment since carbon nanomaterials canact as a medium to transfer the energy of laser beam to the analytes during the ionization step. The polymer monolith was synthesized by in situ thermally initiated polymerization using methacrylic acid (MAA) as the functional monomer and ethylene dimethacrylate (EDMA) as the crosslinker (poly(MAA-EDMA-MWNT) monolith). The results showed that the monolithic coating contained through-pores of approximately 1.6 μm with a narrow size distribution, which could lead to good permeability and favorable mass transfer during the extraction applications. Scanning electron microscopy images of the poly(MAA-EDMAMWNT) monolithic coating. Several parameters affecting the extraction efficiency were optimized, including the pH, salt concentration, organic solvent content of the sample loading solution and the extraction time. The operating parameters of the DART including plasma heating temperature, the distance between the DART outlet and theMS inlet and the laser energy were optimized to obtain the best detection sensitivities of triazines. Conclusion: A novel poly(MAA-EDMA-MWNT) monolith coated Dip-it sampler was prepared in th