小剂量舒芬太尼复合丙泊酚在无痛人流术中的应用观察.docVIP

小剂量舒芬太尼复合丙泊酚在无痛人流术中的应用观察 　　【摘要】 目的：探讨小剂量舒芬太尼复合丙泊酚用于无痛人流麻醉的效果和安全性。方法：选择ASAⅠ～Ⅱ级，自愿行无痛人流的患者130例，按入院先后顺序，随机分为对照组与观察组（n=65）。观察组先予0.1 μg/kg舒芬太尼，2 min后给予丙泊酚1～1.5 mg/kg进行人流麻醉；对照组单纯给予丙泊酚2 mg/kg进行人流麻醉。记录MAP、HR、SpO2变化，丙泊酚的总剂量、意识恢复和定向力恢复时间、术中呼吸抑制和术后宫缩痛的发生率等。结果：与手术前比较，观察组的术中MAP无明显变化，HR和SpO2均明显下降，差异有统计学意义（P0.05）。观察组的丙泊酚总用量、意识恢复时间、定向力恢复时间及宫缩痛发生等均低于对照组，组间差异有统计学意义（P0.05）。结论：小剂量舒芬太尼复合丙泊酚应用于无痛人流的麻醉效果较好，起效迅速，安全平稳，不良反应少，适合在人流术中推广。 　　【关键词】 舒芬太尼； 丙泊酚； 静脉麻醉； 人工流产 　　Low Doses of Sufentanil Combined with Propofol on Anesthesia for Induced Abortion/ZHAO Xiao-bing，LIU Jin-hui.//Medical Innovation of China，2013，10（14）：023-024 　　【Abstract】 Objective：To compare the efficacy and safety of low dose sufentanil combined with propofol on anesthesia for induced abortion.Method：According to the order of admission，130 ASAⅠ-Ⅱpatients of voluntary row painless，were randomly divided into the observation group and control group（n=65）.The observation group was given first 0.1 μg/kg sufentanil 1-1.5 mg/kg crowd anesthetic propofol given after 2 min，control group treated with propofol 2 mg/kg crowd anesthesia.Record changes in MAP，HR，SpO2，the total dose of propofol，recovery of consciousness and orientation recovery time，intraoperative respiratory depression and postoperative contractions pain incidence.Result：Compared with before surgery，MAP was no significant change in the surgery of the observation group，HR and SpO2 were significantly decreased，the difference was statistically significant（P0.05）.The observation group of the total amount of propofol，the recovery of consciousness，orientation recovery time and uterine contraction pain were lower than the control group，the difference was statistically significant between the groups（P0.05）.Conclusion：Small doses of sufentanil combined with propofol anesthesia is better applied to painless onset is rapid，safe and stable，and less adverse reactions，suitable for use in abortion promotion. 　　【Key words】 Sufentanil； Propofol； Intravenous anesthesia； Abortion