Environmental Hormone Research Progress pesticide methoxychlor.docVIP

 PAGE \* MERGEFORMAT 23 Environmental Hormone Research Progress pesticide methoxychlor Of: Li Heng, Shen Xiu Wei, Zhuang Xiuxiu, Hu Guoxin, Ge Ren Shan [Key Words] environmental hormone; methoxychlor; reproductive system; toxicity; review literature In recent years, been detected in food and drinking water to pesticide residues, some pesticides, such as organochlorine pesticides have been shown to be carcinogenic to humans and interfere with the role of the endocrine system. China is a big country of pesticides now in use of pesticides organochlorine pesticides accounted for a large proportion. frequently used organochlorine pesticides are DDT, BHC and DDT analogues methoxychlor (MXC), B DDT and so on. As a structural analogue of DDT, MXC biological activity roughly the same range and DDT. because of their accumulation of fat in the body or secreted into the milk in the trend of smaller, or no, it has become a substitute for DDT, widely used in vegetables and fruit trees to control pests. However, in recent years found , MXC longer half-life (gt; 6 months), degradation problems in the environment has a cumulative effect on soil and water in the non-target organisms such as fish and aquatic products have a certain influence. MXC mainly enter the body through the food chain . MXC acute poisoning can cause typical organochlorine poisoning symptoms: irritability of, muscle tremors, appears paroxysmal, tonic convulsions, until death. long-term chronic poisoning can cause neurobehavioral changes, breast, liver morphology and function damage, and reproductive system toxicity. So MXC in recent years widespread concern by the community, has become one of the main research focus. now present the progress of foreign MXC toxicity studies are summarized below. The general physical and chemical properties of 1 MXC MXC also known as methoxychlor, the chemical name is l, 1,1 - trichloro -2-2-- bis (- methoxyphenyl) ethane [1,1,1-tfichloro-2-2-bis (p -methoxy pho