Familial adenomatous polyposis clinicopathologic study.docVIP

 PAGE \* MERGEFORMAT 7 Familial adenomatous polyposis clinicopathologic study [Abstract] Objective To investigate the familial adenomatous polyposis (FAP) of the clinical and pathological features, diagnosis, and differential diagnosis. Methods The clinical data, colonoscopy and pathological observation on two cases of FAP, sum up its characteristics, combined with literature analysis. Results 2 patients were male, aged 19 years and 36 years. The main clinical manifestations of repeated bloody stool, stool pulpy, accompanied by abdominal pain. Endoscopic and pathological examination were FAP. Pathological examination revealed 1 case: individual polyps had severe glandular dysplasia, cancer. Conclusions FAP high rate of malignancy, diagnostic reliance on clinical, colonoscopy, pathological combination of three aspects. [Keywords:] adenomatous polyposis, colon; pathology, clinical Familial adenomatous polyposis (FAP) is a rare familial and hereditary colorectal polyposis, is a precancerous disease, but its high rate of cancer, if not treated, will eventually be nearly 100% of cancer [1]. Our hospital in 1990 and 2007 have encountered two cases of foreign inspection FAP, are combined review of the literature, its clinicopathological features, differential diagnosis and treatment were analyzed. 1 Data and methods 1.1 The clinical data of cases of a male patient, 19 years old. No obvious incentive for more than two years of repeated bloody, bright red or dark red, attached to the surface or seepage miscellaneous stool which stool slightly pulpy, accompanied by mild abdominal pain. Colonoscopy and do a local hospital pathological investigation showed FAP. In order to further treatment, gradually come to my hospital. Patients, their father had a family history of colon polyps in patients surgical history. Surgery See: All colon polyps of varying sizes filled with diffuse, rice and Tai peanuts large pedunculated or sessile, the number 500 ~ 600 or so, to the rectu