HPLC Determination of compound furazolidone enema content of procaine hydrochloride.docVIP

 PAGE \* MERGEFORMAT 11 HPLC Determination of compound furazolidone enema content of procaine hydrochloride 【Abstract】 Objective To establish a high-performance liquid chromatography (HPLC) Determination of furazolidone compound in the enema fluid content of procaine hydrochloride. Method to establish high-performance liquid chromatography (HPLC) Determination of compound furazolidone enema content of procaine hydrochloride. The results of procaine hydrochloride in the 10.48 ~ 52.40 μg * ml-1 concentration range a good linear relationship, r = 0.999 9, the recovery rate (n = 9) to 100.1% (RSD = 1.1%). Conclusion The method of high sensitivity, wide linear range, with high specificity, rapid and simple, reproducible, suitable for the assay of the preparation and quality control. Keywords: compound furazolidone enema high performance liquid chromatography assay Compound furazolidone enema for my hospital treatment of acute and chronic colitis, the experience of side (070201,070202,070203), from furazolidone, procaine hydrochloride, commonly used drugs such as composition, compatibility is reasonable, curative effect, the application easy and no significant adverse reaction. At present, the compound furazolidone enema no quality standards of procaine hydrochloride by HPLC quality control, the author high performance liquid chromatography compound furazolidone enema content of procaine hydrochloride, to obtain satisfactory results, are reported are as follows. An instrument and reagent SSI Scientific Systems, Inc. high-performance liquid chromatography; Mettler AG135 Electronic Balance; procaine hydrochloride reference substance (content 99.3%). Compound furazolidone enema (self-control, batch number: 070201,070202,070203). Methanol for chromatography pure; water re-distilled water, other reagents were analytical pure. 2 Methods and Results 2.1 Chromatographic conditions and system suitability test Colum