Hyperbaric oxygen in neonatal hypoxic ischemic encephalopathy of.docVIP

 PAGE \* MERGEFORMAT 8 Hyperbaric oxygen in neonatal hypoxic ischemic encephalopathy of [Abstract] neonatal hypoxic ischemic encephalopathy (HIE is one of the main causes of child disability. With the rapid development of perinatal medicine and neonatal intensive care units throughout the hospital (NICU of the establishment, HIE’s survival rate increase, but the occurrence of severe HIE survivors the incidence of permanent brain dysfunction remains high. current nutrition brain cells growing number of drug therapy, and with hyperbaric oxygen (HBO’s widely used in clinical practice, the the treatment of HIE has also been much attention now to the pathogenesis of HIE and the basic principles of HBO treatment of HIE to make a elaboration. [Keywords:] hyperbaric oxygen hypoxic ischemic encephalopathy Neonatal hypoxic ischemic encephalopathy (HIE is fetal distress, neonatal asphyxia due to other reasons hypoxic-ischemic brain lesions, neonatal brain injury is the most common perinatal causes, pathogenesis is extremely complex, lack of Oxygen is the basis of the pathogenesis of HIE. hyperbaric oxygen (HBO treatment of HIE can cause rapid improvement for brain and whole body tissue hypoxia [1], thus using HBO therapy has a significant effect HIE. now to the pathogenesis of HIE and the simple principle of HBO treatment below. 1 HIE in the pathogenesis of 1.1 When the hypoxic-ischemic cerebral blood flow changes as a partial or chronic, the body appears compensatory redistribution of blood to ensure the heart, brain and blood supply. With prolonged hypoxia, the loss of compensatory mechanisms, cerebral blood flow in the final due to impaired heart function, the decline in systemic blood pressure plummeted, appears to re-allocate the 2nd blood flow, cerebral hemispheres, decreased blood flow to ensure that the metabolism of the most productive areas, such as the basal ganglia, brain stem, thalamus and cerebellum of the blood supply. sagittal area of #8203;