Metabolomics technology and the analysis of TCM.docVIP

 PAGE \* MERGEFORMAT 17 Metabolomics technology and the analysis of TCM [Keywords:] metabolomics, TCM, genomics, proteomics Metabolomics (metabonomics) is the second genomics, transcriptomics and proteomics, after a newly developed discipline is an important component of systems biology. Metabolomics main biological material caused by exogenous pathological physiological responses, as well as genetic variation in the response and the dynamic changes of endogenous metabolites, it is through body fluids and tissues of biological change over time to detect the metabolites, identification, quantification and classification, and pathophysiology of these metabolic processes information associate in biological events, to monitor chemical changes in living cells. genomics and proteomics and protein levels, respectively, from the gene to explore the activities of life, and in fact many of the cell life activity is associated with the metabolite, is affected by metabolic material control. gene and protein expression are closely linked, and the metabolites are more a reflection of the environment in which the cells, which in turn with the nutritional status of cells, drugs and other external factors are closely related. Therefore, some scholars believe that genomics and proteomics to explain events that may occur, and metabolomics reflects what has really happened [1]. Metabolomics emphasis on the human body as a complete system to study, through the determination of various body composition of metabolites in body fluids to understand and reflect changes in metabolic networks of human diseases and drug effects in the changes under the law. This reveals the complexity of disease mechanisms and drug metabolism has unique advantages, and Traditional Chinese Medicine the overall concept, the system concept and Differential Treatment of thinking is very consistent, but also with the Chinese emphasis on man and nature, man and society and the universal human connection a