Naloxone observation of 38 cases of acute alcoholism.doc

 PAGE \* MERGEFORMAT 7 Naloxone observation of 38 cases of acute alcoholism Of: Wang Qiao, Zhang Yuebin, Yu-Long Ma, Liu Hui, Zhang Kedong, Chen Yuefen [Abstract] of Naloxone clinical efficacy of treatment of acute alcoholism, 58 cases of non-diabetic patients with alcoholism information. 38 patients in routine gastric lavage, fluid replacement, protection of gastric mucosa, acid and other treatment given naloxone on the basis of ketone 0. 4mg bolus, severe patients can be reused 30min interval 1, then give 5% GS 250mL + naloxone 0. 8mg intravenous infusion, another 20 patients using only conventional treatment. results in patients treated with naloxone symptoms improved significantly, recovery time was significantly earlier (P lt;0. 05). naloxone suggest safe and effective treatment of acute alcoholism. [Keywords:] naloxone, acute alcoholism, clinical efficacy Present hazards caused by the alcohol, increasing hospitalization rates of alcohol dependence. Alcoholic pituitary hypothalamic releasing factor to promote the release of a large number of endogenous opioids, causing neurological disorders and organ damage, severe respiratory and may circulatory failure. naloxone for the hydroxyl -2-- hydrogen morphine derivatives as opioid receptor specific antagonist [1]. as of Naloxone clinical efficacy of treatment of acute alcoholism, analyzed 58 cases of non-diabetic patients with alcoholism information. which 38 patients were given naloxone, and the other 20 patients using only conventional treatment, are as follows. 1 Subjects and methods 1.1 Selection Criteria History of excessive alcohol consumption before onset, breathing, vomit, the smell of ethanol in the central nervous system excitatory or inhibitory, with ataxia, or lethargy and other symptoms of severe poisoning, who was unconscious, remove drugs, chemicals and other reasons gas cause drowsiness, coma, no other complications. According to the clinical level of alcoholism is divided i