PAI-1 4G-5G gene polymorphism and severe acute respiratory syndrome after bone necrosis.docVIP

下载本文档

3
0
约 11页
2017-05-06 发布于浙江
举报
版权申诉

PAI-1 4G-5G gene polymorphism and severe acute respiratory syndrome after bone necrosis.doc

1、本文档共11页，可阅读全部内容。
2、原创力文档（book118）网站文档一经付费（服务费），不意味着购买了该文档的版权，仅供个人/单位学习、研究之用，不得用于商业用途，未经授权，严禁复制、发行、汇编、翻译或者网络传播等，侵权必究。
3、本站所有内容均由合作方或网友上传，本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺！文档内容仅供研究参考，付费前请自行鉴别。如您付费，意味着您自己接受本站规则且自行承担风险，本站不退款、不进行额外附加服务；查看《如何避免下载的几个坑》。如果您已付费下载过本站文档，您可以点击这里二次下载。
4、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等，请点击“版权申诉”（推荐），也可以打举报电话：400-050-0827(电话支持时间：9:00-18:30)。
5、该文档为VIP文档，如果想要下载，成为VIP会员后，下载免费。
6、成为VIP后，下载本文档将扣除1次下载权益。下载后，不支持退款、换文档。如有疑问请联系我们。
7、成为VIP后，您将拥有八大权益，权益包括：VIP文档下载权益、阅读免打扰、文档格式转换、高级专利检索、专属身份标志、高级客服、多端互通、版权登记。
8、VIP文档为合作方或网友上传，每下载1次，网站将根据用户上传文档的质量评分、类型等，对文档贡献者给予高额补贴、流量扶持。如果你也想贡献VIP文档。上传文档

PAI-1 4G-5G gene polymorphism and severe acute respiratory syndrome after bone necrosis

PAI-1 4G/5G gene polymorphism and severe acute respiratory syndrome after bone necrosis Abstract Determination of severe acute respiratory distress syndrome (SARS) bone necrosis after fibrinolysis in patients with a low tendency and plasminogen activator inhibitor PAI-related genes PAI-4G/5G gene polymorphisms and Chinese post-SARS osteonecrosis of the relationship between in order to facilitate non-traumatic osteonecrosis of the early diagnosis and screening of susceptible populations. [Method] 61 patients with post-SARS osteonecrosis in patients with cubital vein blood taken fasting. Another 52 people called to remove the healthy controls, the application of coagulation instrument, enzyme-linked immunosorbent assay (ELISA) were measured PAI value, and application of solid-phase PCR oligonucleotide ligation assay (SPOLA) Determination of PAI-1 gene 4G/5G polymorphism . [Results] SARS osteonecrosis in patients with post-PAI significantly abnormal PAI (15  64 ± 13  85) U / ml VS (7  96 ± 4  27) U / ml, PAI-1 gene 4G/4G in bone necrosis of the crowd higher, but no statistical differences in plasma PAI activity and the 4G/4G homozygous genotype closely related. [Conclusion] SARS osteonecrosis in patients with post-target abnormal coagulation, PAI osteonecrosis risk factors can be used as screening targets. PAI-1 gene 4G/4G people may be genetic markers of bone necrosis. Keywords: Osteonecrosis plasminogen activator inhibitor Abstract [Objective] To explore the correlation between and post-severe acute respiratory symptom (SARS) patients with osteonecrosis, investigate the etiology of post-SARS osteonecrosis, and select the sensitive molecular symbols for early diagnosis and distinguish the high risk population  [Method ] The studied subjects were divided into two groups  Totally 62 post-SARS patients with osteonecrosis was one group, and 52 age and sex matched healthy people was as normal controlled group  Empty stomach blood samples from cubital veins