Research on the progress of intestinal amoebiasis.docVIP

 PAGE \* MERGEFORMAT 11 Research on the progress of intestinal amoebiasis Keywords:: Intestinal amoebiasis Entamoeba histolytica gene encoding isozyme Intestinal amoebiasis by Entamoeba histolytica (Entamoeba histolytica) caused by gastro-intestinal diseases. The world each year there are at least 4 to 11 million people died of severe amebic colitis and (or) parenteral abscess, but there are also long been aware that many people are infected with Entamoeba histolytica is not after the onset of symptoms, infection can be natural removal. Brumpt in 1925 raised the so-called Entamoeba histolytica should be divided into two separate species. Way for the Entamoeba dysenteriae, can cause intestinal amoebiasis; another way for the Entamoeba dispar, does not cause disease. However, Brumpt hypothesis has not been that people have long recognized. Since the 70s, with the right of pathogenic Entamoeba histolytica in-depth research, more and more evidence that the Entamoeba histolytica exist two separate populations, they are exactly the same shape, but the letter disease of this very differently. 1, two groups of Entamoeba histolytica isozymes have a clear and stable differences in Sargeaunt [1] analyzed and compared more than 6,000 from around the world Entamoeba histolytica isolates isozymes. According to glucose mutase (PGM), glucose phosphate isomerase (GPI), L-malic acid: Coenzyme Ⅱ oxide reductase (ME) and hexokinase (HK) 4 isozymes electrophoresis zone number distribution and electrophoretic speed, all the insect strains are divided into a number of enzymes strains of groups: From the symptoms, serum anti-amebic antibody-positive patients with insect strains isolated strains belong to group of enzymes Ⅱ , Ⅵ , Ⅶ , Ⅺ , Ⅻ , Ⅺ Ⅴ other six groups, is the pathogenic species Entamoeba histolytica, which was marked by a β PGM zone, with no α , HK fastest electrophoretic; from asymptomatic, serum antibody-negative persons with a capsule strains were isolated from t