Traditional Chinese Medicine Research on anti-atherosclerosis Review.docVIP

 PAGE \* MERGEFORMAT 30 Traditional Chinese Medicine Research on anti-atherosclerosis Review Abstract Traditional Chinese Medicine anti-atherosclerosis (AS) to obtain the exact results. Major research in the following aspects: 1, adjusting the lipid metabolism of links; 2, anti-vascular mechanism of smooth muscle cell proliferation; 3, protection of vascular endothelial cell research; 4, anti-inflammatory reaction; 5, inhibit platelet adhesion and secretion studies. Chinese medicine also AS-related gene expression play a role and influence. A clinical study of traditional Chinese medicine treatment of AS has also made some progress. Keywords: atherosclerosis Experimental Research on Traditional Chinese Medicine Atherosclerosis (AS) is a common disease, often involving the heart, brain and blood vessels and other important parts of which led to serious consequences. Because of concurrent cardiac, cerebrovascular accidents and deaths account for mortality in the first place, it is known as the “number one killer.” In recent years, Chinese medicine has made anti-AS study of the exact results, are reviewed below. Traditional Chinese Medicine Research on anti-atherosclerosis 1. To adjust the role of lipid metabolism in part of lipid metabolism disorders, deposition in the arterial intima leading to AS The main reason, therefore, adjust the lipid metabolism is the key to anti-AS. Its role primarily through the following links: ① to reduce absorption of exogenous lipids, including laxative, laxative, plant sterols compete lipid enzymes and polysaccharide combination with bile salts to reduce cholesterol absorption; ② inhibition of lipid synthesis, in particular, inhibit cholesterol synthesis rate-limiting enzyme - HMG coenzyme A reductase, thereby reducing the intracellular synthesis of cholesterol; ③ to promote lipid transfer and clearance, affecting lipid enterohepatic circulation, accelerate its excretion. Different Chinese me