Application of Molecularly Imprinted Polymers for the Analysis of Pesticide Residues in Food—A Highly Selective and Innovative Approach英文文献资料.docVIP

American Journal of Analytical Chemistry, 2011, 2, 16-25 doi:10.4236/ajac.2011.228119 Published Online December 2011 (http://www.SciRP.org/journal/ajac) Application of Molecularly Imprinted Polymers for the Analysis of Pesticide Residues in Food—A Highly Selective and Innovative Approach Raquel Garcia, Maria Jo?o Cabrita, Ana Maria Costa Freitas Instituto de Ciências Agrárias e Ambientais Mediterranicas, Departamento de Fitotecnia, Escola de Ciências e Tecnologia, Universidade de évora, évora, Portugal E-mail: afreitas@uevora.pt Received November 15, 2011; revised December 21, 2011; accepted December 29, 2011 Abstract The increasing application of pesticides for agricultural purposes involves serious risk to the environment and human health due to either exposure or through residues in food and drinking water. Since food safety is of mandatory importance there is a growing interest on the development of selective, simple, rapid, cost-ef- fective and reliable analytical methodologies in order to ensure that pesticides residues should not be found at levels above the established maximum pesticide residue limits (MRLs). In recent years, a new methodol- ogy based on the development of molecularly imprinting polymers (MIPs) allows not only pre-concentration and cleaning of the sample but also selective extraction of the target analyte, which is crucial, particularly when the sample is complex and impurities can interfere with quantification. The scope of this review is to provide a general overview on MIPs field, with emphasis on MIP preparation and its use as sorbents for solid-phase extraction. This paper will be focused on the review of the current state of the art in the use of MIPs as selective materials in molecularly imprinted solid-phase extraction (MISPE) for the analysis of pes- ticide residues from food matrices. A review of preparation and application of MIPs in food matrices, will also be discussed. Keywords: Molecularly Imprinted Polymer, Pe