Number needed to treat = six therapeutic hypothermia following cardiac arrest – an effective and cheap approach to save lives 英文参考文献.docVIP

Available online /content/11/4/162 Commentary Number needed to treat = six: therapeutic hypothermia following cardiac arrest – an effective and cheap approach to save lives Bernd W B?ttiger, Andreas Schneider and Erik Popp Department of Anaesthesiology, University of Heidelberg, Germany Corresponding author: Bernd W B?ttiger, bernd.boettiger@med.uni-heidelberg.de Published: 31 August 2007 Critical Care 2007, 11:162 (doi:10.1186/cc6100) This article is online at /content/11/4/162 ? 2007 BioMed Central Ltd See related research by Pichon et al., /content/11/3/R71 Abstract 2. Induced hypothermia might also benefit unconscious adult patients with spontaneous circulation after out-of- hospital cardiac arrest from a non-shockable rhythm, or cardiac arrest in hospital. 3. A child who regains a spontaneous circulation but remains comatose after cardiopulmonary arrest may benefit from being cooled to a core temperature of 32 to 34°C for 12 to 24 hours. In 2005, the European Resuscitation Council (ERC) guidelines stated: Unconscious adult patients with spontaneous circulation after out-of-hospital ventricular fibrillation cardiac arrest should be cooled to 32 to 34°C for 12 to 24 hours. Patients with cardiac arrest from a non-shockable rhythm, in-hospital patients and children may also benefit from hypothermia. There is no argument to wait. We have to treat the next unconscious cardiac arrest patient with hypothermia. Therapeutic hypothermia influences postresuscitation brain – and other organ – injury in many different ways: it reduces The article “Efficacy of and tolerance to mild induced hypothermia after out-of-hospital cardiac arrest using an endovascular cooling system” by Pichon et al. in the previous issue of Critical Care [1] points to a very relevant health care issue. Only 10% of patients undergoing out-of-