Primary angiosarcoma of the testis report of a rare entity and review of the literature 英文参考文献.docVIP

Diagnostic Pathology BioMedCentral Review Open Access Primary angiosarcoma of the testis: report of a rare entity and review of the literature Henry B Armah*, Uma NM Rao and Anil V Parwani Address: Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA Email: Henry B Armah* - armahh2@; Uma NM Rao - raounm@; Anil V Parwani - parwaniav@ * Corresponding author Published: 2 July 2007 Received: 15 June 2007 Accepted: 2 July 2007 Diagnostic Pathology 2007, 2:23 doi:10.1186/1746-1596-2-23 This article is available from: /content/2/1/23 ? 2007 Armah et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: Primary testicular angiosarcomas are extremely rare, and their clinicopathologic features are not well described. Our objective was to further define the clinical features and pathologic spectra of primary testicular angiosarcomas. Methods: Six previously reported case reports were identified in the English language medical literature using MEDLINE and a subsequent bibliographic search of all pertinent reports and reviews was performed. After excluding 2 cases because they did not involve the testis, we identified 4 previously reported cases of true primary testicular angiosarcoma. We also searched the electronic medical archival records of our institution and identified one additional unreported case of true primary testicular angiosarcomas. Data were extracted on the demographics, predisposing factors, clinical presentation, gross pathology, microscopic pathology, immunophenotype, therapy, and outcomes of each of these 5 cases of true primary testicular angiosarcomas. Results: Primary testicular angiosarcomas