Response to Comparison of laser Doppler imaging, fingertip lacticemy test, and nailfold capillaroscopy for assessment of digital microcirculation in systemic sclerosis - authors reply 英文参考文献.docVIP

Correa et al. Arthritis Research Therapy 2011, 13:302 /content/13/1/302 LETTER Response to: Comparison of laser Doppler imaging, ? ngertip lacticemy test, and nailfold capillaroscopy for assessment of digital microcirculation in systemic sclerosis - authors’ reply Marcelo JU Correa, Luis EC Andrade and Cristiane Kayser* See related letter by Sulli et al., /content/13/1/301, and related research by Correa et al., /content/12/4/R157 We thank Sulli and colleagues [1] for their interest in our article entitled ‘Comparison of laser Doppler imaging, that only Rosato and colleagues [7], who were considered in our original paper, evaluated blood perfusion by means ? ngertip lacticemy test, and nailfold capillaroscopy for of LDI. Moreover, the mechanisms involved in SSc assess ment of digital microcirculation in systemic sclerosis’ vasculopathy are complex, and controversial ? ndings are e LDI method used in our original [2], which was published in a recent issue of Arthritis not surprising Research erapy. Sulli and colleagues commented on study is considered the most promising tool for the study of microvascular blood ? ow. In our study, LDI showed our results regarding the lack of correlation between the laser Doppler imaging (LDI) technique and nailfold lower digital blood ? ow in SSc patients when compared capillaroscopy (NFC) and raised interesting questions. with healthy controls and correlated negatively with We totally agree with the comment that NFC is a ? ngertip lacticemy, allowing objective measurement of powerful tool for the assessment of microvascular blood perfusion. It is also relevant to point out that damage in systemic sclerosis (SSc). Recently, we showed a positive correlation between NFC abnormalities and the Murray and colleagues [4] showed only a weak corre- lation between intercapillary