Sleep duration, vital exhaustion and perceived stress among pregnant migraineurs and non-migraineurs 英文参考文献.docVIP

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Sleep duration, vital exhaustion and perceived stress among pregnant migraineurs and non-migraineurs 英文参考文献.doc

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Sleep duration, vital exhaustion and perceived stress among pregnant migraineurs and non-migraineurs 英文参考文献

Williamsetal.BMCPregnancyandChildbirth2010,10:72 /1471-2393/10/72 RESEARCH ARTICLE OpenAccess Sleepduration,vitalexhaustionandperceived stressamongpregnantmigraineursand non-migraineurs MichelleAWilliams1,2*,SheenaKAurora3,IhunnayaOFrederick2,ChunfangQiu2,BizuGelaye1,SweeMayCripe1 Abstract Background:Migrainehasbeenassociatedwithsleepdisordersinmenandnon-pregnantwomen,butlittleis knownaboutsleepcomplaintsamongpregnantmigraineurs. Methods:Acohortof1,334womenwasinterviewedduringearlypregnancy.Atthetimeofinterviewwe ascertainedparticipants’migrainediagnosisstatusandcollectedinformationaboutsleepdurationbeforeand duringearlypregnancy,daytimesleepiness,vitalexhaustionandperceivedstressduringearlypregnancy. Multivariablelogisticregressionprocedureswereusedtoestimateoddsratios(ORs)and95%confidenceintervals (CIs)ofshort/longsleepduration,excessivedaytimesleepiness,vitalexhaustionandelevatedperceivedstress associatedwithahistoryofmigraine. Results:Approximately19.4%ofthecohort(n=259)reportedhavingamedicaldiagnosisofmigrainepriortothe studypregnancy.Comparedwithwomenwithoutmigraine,themultivariable-adjustedORs(95%CI)among migraineursforshortsleepdurationbeforeandduringearlypregnancywere1.51(1.09-2.09),and1.57(1.11-2.23), respectively.ThecorrespondingOR(95%CI)forlongsleepdurationbeforeandduringpregnancywere1.33 (0.77-2.31)and1.31(0.94-1.83),respectively.Amodestandstatisticallyinsignificantassociationbetweenmigraine historyandexcessivedaytimesleepinessinearlypregnancywasnoted(OR=1.46;95%CI0.94-2.26).Migraineurs hadanincreasedriskofvitalexhaustion(OR=2.04;95%CI1.52-2.76)andelevatedperceivedstress(OR=1.57; 95%CI1.06-2.31).Observedassociationsweremorepronouncedamongoverweightmigraineurs. Conclusions:Thesedatasupportearlierresearchdocumentingincreasedrisksofsleepdisordersamong migraineurs;andextendstheliteraturetoincludepregnantwomen.Prospectivestudiesareneededtomore thoroughlyexplorefactorsthatmediatetheapparentmigraine-sleepcomorbidityamongpregnantwomen. Background showimprove