血液净化联合前列地尔及奥曲肽治疗高脂血症胰腺炎临床探究.docVIP

血液净化联合前列地尔及奥曲肽治疗高脂血症胰腺炎临床探究[摘 要] 目的 研究血液净化（continuous blood purification，CBP）联合前列地尔注射液及醋酸奥曲肽治疗高脂血症胰腺炎的疗效。方法 50例高脂血症胰腺炎患者分成观察组和对照组。对照组：醋酸奥曲肽；观察组：醋酸奥曲肽+前列地尔注射液+CBP。结果 观察组显效率（80.00%）、总有效率（96.00%）高于对照组显效率为（48.00%）、总有效率（68.00%），差异有统计学意义（P＜0.05）；观察组治疗5d后血淀粉酶阴转率为80.00%高于对照组血淀粉酶阴转率48.00%，差异有统计学意义（P＜0.05）。两组不良反应发生率差异无显著性（P＞0.05）。结论 CBP联合前列地尔注射液及醋酸奥曲肽治疗高脂血症胰腺炎疗效可靠，安全，值得临床应用推广。 [关键词] 血液净化；前列地尔；醋酸奥曲肽；高脂血症胰腺炎 [中图分类号] R589.2；R657.5+1 [文献标识码] B [文章编号] 1673-9701（2011）24-95-02 Clinical Research of CBP and Alprostadil and Octreotide Acetate Treatment of Hyperlipoidemia Acute Pancreatit WEI Guijun HU Yi YANG Yong Digesting Internal Medicine Department， the First People’s Hospital in Huzhou City of Zhejiang Province， Huzhou 313000， China [Abstract] Objective To study the efficacy research of CBP and alprostadil and octreotide acetate treatment of hyperlipoidemia acute pancreatit. Methods All 50 cases of hyperlipoidemia acute pancreatit were divided into observation group and control group. Control group： octreotide acetate；Observer Group： octreotide acetate + alprostadil+ CBP. Results Significant efficiency of the observation group 80.00%， the total effective 96.00% bigger than significant efficiency 48.00% the total effective 68.00% of control group， difference was statistically significant （P＜0.05）； Treatment for five days， blood amylase yin turn rate the observation group 80.00% than 48.00% in control group，there was statistically significant difference （P＜ 0.05）. Two groups adverse reaction rate had no significant difference （P＞0.05）. Conclusion CBP and alprostadil and octreotide acetate treatment of hyperlipoidemia acute pancreatit is good efficacy，few adverse reactions，affordable，worth of clinic application promotion. [Key words] CBP；Alprostadil；Octreotide acetate；Hyperlipoidemia acute pancreatit 目前高脂血症胰腺炎的发病率逐年上升，已成为临床急性胰腺炎发生的第二大病因[1]。本文中，笔者采用血液净化（continuous blood purification，CBP）联合前列地尔注射液及醋酸奥曲肽治疗高脂血症胰腺炎，取得较好的疗效，现报道如下。 1 对象与方法 1.1 研究对象 本课题所选病例50