乙醚吸入与戊巴比妥钠腹腔注射联合麻醉的应用.pdfVIP

2008年 1月 中国比较医学杂志 January．2008 第 l8卷 第1期 CHINESE JOURNAL OF COMPARATIVE MEDICINE Vo1．18 No．1 g研究报告 S !； 、!； 、!； 二 、 乙醚吸人与戊巴比妥钠腹腔注射联合麻醉的应用 何 华 (安徽医科大学附属省立医院动物实验室，合肥 230001) 【摘要】 目的 探讨乙醚吸人与戊巴比妥钠联合麻醉应用效果。方法 随机将20只受肝大鼠分成两组，每 组 l0只。A组为单纯的乙醚吸人麻醉对照组，B组先用乙醚吸人作麻醉诱导，再腹腔注射2％戊巴比妥钠作麻醉维 持。观察手术时间、术中追加麻醉次数、术后苏醒时间和死亡率。结果 与B组相比，A组手术时间明显延长(P 0．05)，术中平均需要重复吸人乙醚5±1．63次，以维持麻醉状态。B组术中麻醉平稳，不需要继续给药．两组术后 苏醒时间无显著性差异(P0．05)。结论 乙醚吸人与戊巴比妥钠联合麻醉，可延长麻醉的有效时间，加强麻醉 效果，有效地保证手术的顺利进行。 【关键词】 乙醚；戊巴比妥纳；麻醉 【中图分类号】R614 【文献标识码】A 【文章编号】1671—7856{2008)Ol一0030-02 Application of Anaesthesia with Combined Ether Inhalation and Sodium Pentobarbital Intraperitoneal Injection to Rat Liver Transplantation (Department of Animal Laboratory，Affiliated Provincial hospital，Anhui Medical University，Hefei 230001．China) 【Abstract】 Objective To study the effect of anaesthesia with combined ether inhalation and sodium pentobarbital intraperitoneal injection to rat liver transplantation．Method 20 liver receiving rats were randomly divided into 2 groups，received 2 methods of anaesthesia with ether inhalation(group A，n=10)and ether inhalation plus 2％ sodium pentobarbital intraperitoneal injection(group B，n=10)respectively．The time needed for operation and for recovering consciousness after operation，t}le times of intraoperative anaesthesias and the death rate were obser ed．Results The anaesthesia was more stable in group B than that in group A with no mole intraoperative anaesthesia and a shorter operation time．but no significant difference was found in the