surgical treatment for refractory epilepsy review of patient evaluation and surgical options评估患者的外科治疗难治性癫痫检查和手术的选择.pdfVIP

Hindawi Publishing Corporation Epilepsy Research and Treatment Volume 2011, Article ID 303624, 10 pages doi:10.1155/2011/303624 Review Article Surgical Treatment for Refractory Epilepsy: Review of Patient Evaluation and Surgical Options Kristen M. Kelly and Steve S. Chung Department of Neurology, Barrow Neurological Institute, St. Joseph’s Hospital and Medical Center, 500 West Thomas Road, Suite 720, Phoenix, AZ 85013, USA Correspondence should be addressed to Kristen M. Kelly, kristen.kelly@ Received 2 October 2010; Revised 4 February 2011; Accepted 22 March 2011 Academic Editor: Giangennaro Coppola Copyright © 2011 K. M. Kelly and S. S. Chung. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Treatment of epilepsy often imposes an exposure to various antiepileptic drugs and requires long-term commitment and compliance from the patient. Although many new medications are now available for the treatment of epilepsy, approximately 30% of epilepsy patients still experience recurrent seizures and many experience undesirable side effects. Treatment of epilepsy requires a multidisciplinary approach. For those patients with medically refractory seizures, surgical treatment has increased in prevalence as techniques and devices improve. With increased utilization, proper patient selection has become crucial in evaluating appropriateness of surgical intervention. Epilepsy syndromes in which surgery has shown to be effective include mesial temporal sclerosis, cortical dysplasia, many pediatric epilepsy syndromes, and vascular malformations. Monitoring in an epilepsy moni