原创力文档abc transporters as multidrug resistance mechanisms and the development of chemosensitizers for their reversalabc转运蛋白和多药耐药性机制和发展chemosensitizers逆转.pdfVIP
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abc transporters as multidrug resistance mechanisms and the development of chemosensitizers for their reversalabc转运蛋白和多药耐药性机制和发展chemosensitizers逆转
C
CANCER CELL
INTERNATIONAL
Cancer Cell International BioMed Central
Review Open Access
ABC transporters as multidrug resistance mechanisms and the
development of chemosensitizers for their reversal
Cheol-Hee Choi*
Address: Research Center for Resistant Cells, Chosun University Medical School, 375 Seosuk-dong, Dong-gu, Gwangju 501-759, South Korea
Email: Cheol-Hee Choi* - chchoi@chosun.ac.kr
* Corresponding author
Published: 04 October 2005 Received: 20 March 2004
Accepted: 04 October 2005
Cancer Cell International 2005, 5:30 doi:10.1186/1475-2867-5-30
This article is available from: /content/5/1/30
© 2005 Choi; licensee BioMed Central Ltd.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0),
which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
ABC transporterbioavailabilitychemosensitizerdprotein. rug resistanceP-glycoproteinmultidrug resistance associated proteinbreast cancer resistance
Abstract
One of the major problems related with anticancer chemotherapy is resistance against anticancer
drugs. The ATP-binding cassette (ABC) transporters are a family of transport
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