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influence of postpartum onset on the course of mood disorders影响产后出现的情绪障碍
BMC Psychiatry BioMed Central
Research article Open Access
Influence of postpartum onset on the course of mood disorders
Alessandro Serretti*, Paolo Olgiati and Cristina Colombo
Address: Department of Psychiatry, Vita-Salute University, San Raffaele Institute, Milan, Italy
Email: Alessandro Serretti* - Serretti.Alessandro@hsr.it; Paolo Olgiati - polgiati@; Cristina Colombo - Colombo.Cristina@hsr.it
* Corresponding author
Published: 26 January 2006 Received: 23 August 2005
Accepted: 26 January 2006
BMC Psychiatry 2006, 6:4 doi:10.1186/1471-244X-6-4
This article is available from: /1471-244X/6/4
© 2006 Serretti et al; licensee BioMed Central Ltd.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0),
which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Background: To ascertain the impact of postpartum onset (PPO) on the subsequent time course
of mood disorders.
Methods: This retrospective study compared per year rates of excited (manic or mixed) and
depressive episodes between fifty-five women with bipolar (N = 22) or major depressive (N = 33)
disorders with first episode occurring postpartum (within four weeks after childbirth according to
DSM-IV definition) and 218 non-postpartum onset (NPPO) controls. Such patients had a traceable
illness course consisting of one or more episodes alternating with complete symptom remi
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