子宫螺旋动脉血流参数联合血清孕酮、β-HCG检测预测早期先兆流产的临床研究.docVIP

精品论文 参考文献 子宫螺旋动脉血流参数联合血清孕酮、β-HCG检测预测早期先兆流产的临床研究 文细娇 陈燕桢 陈燕君 　　（潮州市湘桥区妇幼保健院 广东潮州 521000） 　　【摘要】目的：探讨子宫螺旋动脉血流参数联合血清孕酮、beta;-HCG检测预测早期先兆流产的临床研究价值。方法：选取我院2011年至2013年就诊的具有先兆流产临床症状的120例患者，根据临床症状及妊娠结局分为先兆流产组93例，停经时间5～8周；难免流产组27例，停经时间6～8周。另选取120例正常妊娠妇女做对照组，停经时间5～8周，分别比较三组患者子宫螺旋动脉血流参数、血清孕酮、beta;-HCG及联合检测结果。结果：先兆流产组子宫螺旋动脉RI、PI值较对照组升高，差异明显，具有统计学意义（P＜0.05）；难免流产组较先兆流产组RI值更高，差异明显，具有统计学意义（P＜0.05）。正常组及先兆流产组血清孕酮、beta;-HCG值均显著高于难免流产组（P＜0.05），具有统计学意义；子宫螺旋动脉RI联合孕酮、beta;-HCG检测特异性及准确性较其他单独检测指标升高，差异明显，具有统计学意义（P＜0.05）。结论：联合子宫螺旋动脉血流参数、血清孕酮及beta;-HCG检测可提高早期先兆流产的检出率，且能在一定程度上反映先兆流产预后，为临床提早展开治疗提供有力依据，值得临床推广。 　　【关键词】先兆流产 子宫螺旋动脉血流 孕酮 beta;-HCG 　　【中图分类号】R446 【文献标识码】A 【文章编号】1672-5085（2014）11-0070-02 　　Clinical Research of Combining Uterine Spiral Artery Blood Flow Parameters，Serum Progesterone and ?-HCG Test in Prediction Outcome of Early Threatened Abortion 　　 WEN Xijiao, CHEN Yanjun, CHEN Yanzhen 　　(Maternity and Infant Health Hospital of Xiangqiao District, Chaozhou City,521000) 　　【Abstract】objective: To investigate the clinical value of uterine spiral artery blood flow parameters，serum progesterone and ?-HCG Test in prediction outcome of early threatened abortion. Methods: 120 cases of threatened abortion patients were selected in our hospital from 2011 to 2013,among whom 93 cases of threatened abortion were divided into the first group with a 5 ～ 8 weeks of menopause , according to the clinical symptoms and pregnancy outcome; 27 cases of Inevitable abortion into the second group with a 6 ～ 8 weeks menopause. Another 120 cases of normal pregnant women(the third group) with a 5 ～ 8 weeks of menopause were also selected to compare the results of examing alone with the results of joint detection .Results: The uterine spiral artery RI, PI of the first group are comparatively higher than the other groups with statistical significance (P lt; 0.05);The uterine spiral artery RI of the second group is even higher than the first gro