黄芪精口服液对小儿慢性气管炎患者血清IL-6, IL-8和SOD水平的影响.docVIP

精品论文 参考文献 黄芪精口服液对小儿慢性气管炎患者血清IL-6, IL-8和SOD水平的影响 温晓春1 蔡爱东2 (1南京医科大学附属南京儿童医院药剂科 210008；2南京医科大学附属南京儿童医院急诊科 210008) 【摘要】目的:探讨了黄芪精口服液对小儿慢性气管炎患者血清IL-6，IL-8和SOD水平的影响。方法： 应用放射免疫分析法和化学法测定了31例小儿慢性气管炎患者血清IL-6，IL-8和SOD含量，并与35名正常健康儿作比较。结果：小儿慢性气管炎患者在治疗前血清IL-6，IL-8水平均非常显著地高于正常儿组(Plt;0.01),而SOD水平又非常显著地低于正常儿组(Plt;0.01),经治疗2周后，血清IL-6，IL-8和SOD水平与正常人比较无显著性差异(Pgt;0.05)。结论： 黄芪精口服液对小儿慢性气管炎有较好的防治作用，有一定的临床实用价值。 【关键词】 小儿慢性气管炎 黄芪精口服液 白细胞介素-6 白细胞介素-8 超氢化物歧化酶 【中图分类号】R725.6 【文献标识码】A 【文章编号】2095-1752（2014）18-0083-02 Effect of oral preparation of Astragalus Membranaceous on Serum IL-6, IL-8 and SOD levels in patients with children chronic Bronchialitis. Organization: Nanjing childrenrsquo;s hospital Name: Wen XiaoChun 【Abstract】objective: to explore the therapeutic effect of oral liquid preparation of astragalus mermbranaceous in children chronic bronchialitis with Special reference of Serum IL-6, IL-8 and SOD levels, Methods: Serum IL-6, IL-8( with RIA), Serum SOD(with chemistry) Levels were measured in 31 patients with chronic brochialitis as well as in 35 controls.Results: before treatment, serum IL-6,IL-8 levels in the patients were significantly higher than those in controls (Plt;0.01), but Serum SOD levels were significantly lower(Plt;0.01), after treatment for 2 weeks, the Serum IL-6, IL-8 and SOD levels were not much different from those in controls(Pgt;0.05).Conclusions: oral Liquid preparation of astragalus membranaceous were therapeutically useful for chronic bronchialitis in patients with correction of the serum IL-6, IL-8 and SOD levels. 【Key words】chronic bronchialitis of childre Astragalus membranaceous Interleukin-6 (IL-6) Interleukin-8 (IL-8) Superoxide dismutase(SOD) 儿童慢性支气管炎为儿童常见的一种呼吸道疾病，严重地危害儿童的身心健康，近年来颇受临床和科研工作者的关注[1]。IL-6，IL-8为一种重要的炎性细胞因子[2]。SOD与疾病的关系十分密切[3]。对治疗小儿慢性气管炎临床上仍以抗感染，解痉挛和缓解呼吸道症状为主。本文应用口服黄芪精治疗31例小儿慢性气管炎，观察了治疗前后血清IL-6，IL-8和SOD水平的变化，现将结