分化抑制蛋白id和hiv1整合酶抑制剂的结构分子生物学研究-study on structural molecular biology of differentiation inhibitor id and hiv - 1 integrase inhibitor.docx
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分化抑制蛋白id和hiv1整合酶抑制剂的结构分子生物学研究-study on structural molecular biology of differentiation inhibitor id and hiv - 1 integrase inhibitor
目录英文缩略语表.......................................................................................................4中文摘要...............................................................................................................5英文摘要...............................................................................................................7前言.......................................................................................................................9第一部分ID蛋白N端保守域结构预测及基因突变体的构建11中文摘要.................................................11英文摘要.................................................12前言....................................................13材料和方法...............................................13结果....................................................15讨论....................................................21第二部分含有没食子酰基儿茶素作为HIV-1整合酶抑制剂的研究...25中文摘要25英文摘要.................................................27前言....................................................29材料和方法...............................................31结果....................................................33讨论....................................................44综述一结构分子生物学现状.......................................................................51综述二天然化合物抑制HIV整合酶的研究进展57个人简介.............................................................................................................61攻读博士学位期间第一作者发表文章.............................................................62发表中文文章一.................................................................................................63发表中文文章二.................................................................................................71发表英文文章.....................................................................................................75致谢...............................................................................................................108英文缩略语表英文缩写英文全名中文译名NMRNuclearmagnetresonance核磁共振EGCGEpigallocatechingallate表没食子儿茶素没食子酸酯ECGEpicatechingallate表儿茶素没食子酸酯I
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