PM2.5浓度在小儿支气管哮喘中临床分析.docVIP

PM2.5浓度在小儿支气管哮喘中临床分析 　　【摘要】 目的：探讨大气颗粒物（PM2.5）浓度在小儿支气管哮喘中的作用，为哮喘发病机制提供临床指导。方法：选取宜宾市第一人民医院门诊及住院患儿（2014年2月-2015年6月），分为两组，大气颗粒物（PM2.5）高浓度组100例，大气颗粒物（PM2.5）低浓度组100例；观察两组患儿外周血的嗜酸性粒细胞计数数量（EOS值）、哮喘发病率、1个月内再次发病率、3个月再次发病率、半年再次发病率。结果：大气颗粒物（PM2.5）高浓度组较大气颗粒物（PM2.5）低浓度组EOS值、发病率、1个月内再次发病率、3个月再次发病率、半年再次发病率明显高，差异有统计学意义（P0.05）。结论：大气颗粒物（PM2.5）能使哮喘患儿EOS值、短期内再次发病率明显升高。 　　【关键词】 大气颗粒物（PM2.5）； 小儿哮喘； 临床分析 　　doi：10.14033/j.cnki.cfmr.2017.15.084 文献标识码 B 文章编号 1674-6805（2017）15-0151-03 　　Clinical Analysis of PM2.5 Concentration in Infantile Asthma/REN Yan.//Chinese and Foreign Medical Research，2017，15（15）：151-153 　　【Abstract】 Objective：To investigate the effect of PM2.5 concentration in infantile asthma to provide clinical guidelines for the treatment of asthma pathogenesis.Method：Selected the First People’s Hospital of Yibin outpatients and hospitalized children（February 2014-June 2015） and divided into two groups.Atmospheric particulate matter（PM2.5） in children with high concentrations group of 100 cases.Atmospheric particulate matter（PM2.5） in children with low concentrations of 100 cases.Observed the incidence of asthma in two groups of children，the number of eosinophil counts in peripheral blood（EOS value），morbidity，incidence of morbidity in one month，three months，six months again.Result：Compared with atmospheric particulate matter（PM2.5） in children with low concentrations，EOS value，morbidity，incidence of morbidity in one month，three months，six months again increased more significant than atmospheric particulate matter（PM2.5） in children with high concentrations，the differences were statistically significant（P0.05）.Conclusion：Atmospheric particulate matter（PM2.5） can significantly increase the EOS value and the incidence of asthma in children once again in the short term. 　　【Key words】 Atmospheric particulates（PM2.5）； Infantile asthma； Clinical analysis 　　First-author’s address：Yibin City Fourth People’s Hospital，Yibin 644002，China 　　小儿支气管哮喘为儿科呼吸道常见病及多发病，其典型临床症状是在可逆性气流受限，常见临床表现为