TCTHPV和阴道镜在宫颈癌筛查中应用.docVIP

TCTHPV和阴道镜在宫颈癌筛查中应用 　　doi：10.3969/j.issn.1007-614x.2014.4.10 　　摘 要 目的：探讨TCT、HPV以及阴道镜在宫颈筛查中的临床应用价值。方法：收治妇科门诊体检及就诊的患者1468例，分为A组和B组，A组的784例采取TCT、阴道镜筛查方法，B组的684例采取TCT、HPV和阴道镜的筛查方法，根据宫颈活检病理诊断结果作为标准，对比分析筛查效果。结果：A组的784例中筛出CIN及宫颈癌21例（2.68%）；B组的684例筛出CIN及宫颈癌45例（6.58%），两组比较差异有统计学意义（P0.01）。结论：采取TCT、HPV联合阴道镜筛查的方法能够有效提高宫颈癌前病变的阳性检出率，对于宫颈癌的预防和早期诊治具有重要的应用价值。 　　关键词 TCT HPV 阴道镜 宫颈癌筛查 　　Application of TCT，HPV and colposcopy in screening of cervical cancer 　　Chen Chunjuan 　　Department of gynaecology of Jiaozuo Peoples Hospital of Henan Province，454002 　　Abstract Objective：To investigate the clinical application value of TCT，HPV and colposcopy in screening of cervical cancer.Methods：1468 patients in the out-patient gynecological examination and treatment were divided into group A and group B.A group of 784 patients were screened with TCT and colposcopy，684 cases in B group adopted TCT，HPV and colposcopy in screening method.Effect of screening was analyzed according to the results of pathological diagnosis of cervical biopsy.Results：In 784 cases of A group，there were 21 cases（2.68%） of CIN and cervical cancer.In 684 cases of B group，there were 45 cases（6.58%） of CIN and cervical cancer.The difference between the two groups was significant（P0.01）.Conclusion：Taking the method of TCT，HPV combined with colposcopy in screening cervical precancerous lesions can effectively improve the positive rate，and has important application value for prevention and early diagnosis and treatment of cervical cancer. 　　Key words TCT；HPV；Colposcopy；Cervical cancer screening 　　宫颈癌是女性生殖系统发病率较高的恶性肿瘤之一，近年来发病率在不断升高，发病人群也呈年轻化趋势。目前宫颈癌的发病率及病死率仅次于乳腺癌，严重威胁着女性的身心健康。研究资料表明，宫颈浸润癌患者的5年生存率接近70%，而早期癌的5年生存率可以达到90%，CIN患者的5年生存率基本接近100%[1]。由此可见，早期进行宫颈癌的准确筛查对于宫颈癌预防及治疗具有重要意义。通过对我院妇科门诊体检及就诊的1468例采取TCT、HPV联合阴道镜的筛查方法，取得了理想的效果，现报告如下。 　　资料与方法 　　2011年1月-2013年7月诊治体检及就诊的患者1468例，全部患者被随机分为A组和B组，其中A组784例，年龄23～61岁，平均40.2岁；B组684例，年龄22～60岁，平均39.6岁，全部体检及就诊的妇女都存在性生活史。 　　方法：对所有体检或就诊的患者常规询问病史，特别询问了解是否存在高危性行为。A组的784例对其进行TCT检查，之后依照TCT检查结果