Sysmex XT―1800i异型淋巴细胞提示信息对EB病毒感染临床价值探讨.docVIP

Sysmex XT―1800i异型淋巴细胞提示信息对EB病毒感染临床价值探讨 　　[摘要] 目的 探讨Sysmex XT-1800i血液分析仪异型淋巴细胞提示信息对EB病毒感染的临床价值。 方法 选取2013年1月～2014年8月Sysmex XT-1800i血液分析仪有异型淋巴细胞提示信息的300例门诊或住院患者作为研究对象。所有患者的标本于2 h内涂片、瑞氏染色、镜检，同时检测血清EBV IgM抗体。 结果 显微镜法确认的异型淋巴细胞阳性率为79.3%。仪器法和显微镜法检测异型淋巴细胞均为阳性组的血清EBV IgM阳性率为87.9%，显著高于仪器法阳性而显微镜法阴性组的19.1%，差异有统计学意义（P0.05）。异型淋巴细胞低比例组的EBV IgM抗体阳性率为75.9%，显著低于高比例组的94.6%，差异有统计学意义（P0.01）。 结论 Sysmex XT-1800i血液分析仪异型淋巴细胞提示信息具有重要临床价值，能够提示EB病毒感染。 　　[关键词] XT-1800i；血液分析仪；异型淋巴细胞；提示信息；EB病毒 　　[中图分类号] R446.11+3 [文献标识码] A [文章编号] 1674-4721（2015）01（b）-0137-03 　　Clinical value discussion of atypical lymphocyte alerting information from Sysmex XT-1800i for the EB virus infection 　　WANG Yu1 MOU Hong-lan2 　　1.Clinical Laboratory，Hospital of Civil Aviation Flight University in China，Guanghan 618307，China；2.Clinical Laboratory，People′s Hospital of Pixian County in Chengdu City，Pixian 611730，China 　　[Abstract] Objective To explore the clinical value of atypical lymphocyte alerting information from Sysmex XT-1800i for the EB virus infection. Methods 300 outpatients or inpatients with atypical lymphocyte alerting information from Sysmex XT-1800i from January 2013 to August 2014 were selected as the research object.All specimens were smeared and detected with Wright′s staining for microscopy，and serum EBV IgM antibody was detected in 2 hours. Results Positive samples of atypical lymphocytes confirmed by microscopy was 79.3%.The positive rate of serum EBV IgM in instrumental method（+） and microscopy（+） group was 87.9%，which was higher than 19.1% in instrumental method（+） but microscopy（-） group，with significant difference（P0.05）.The positive rate of EBV IgM antibody in low proportion group was 75.9%，which was lower than 94.6% in high proportion group，with significant difference（P0.01）. Conclusion Atypical lymphocyte alerting information of Sysmex XT-1800i has important clinical value，which can prompt the infection of EB virus. 　　[Key words] XT-1800i；Hematology analyzer；Heterotypic lymphocyte；Alertin