中药内服结合外敷气瘿穴治疗甲状腺良性结节临床研究.docVIP

中药内服结合外敷气瘿穴治疗甲状腺良性结节的临床研究 　　[摘要] 目的 观察散结1号方内服结合局部外敷气瘿穴治疗甲状腺良性结节的临床效果。 方法 选取广州市增城区中医医院2014年7月～2015年7月收治的甲状腺良性结节患者80例，将其随机分为两组。治疗组40例内服中药散结1号方，加局部外敷散结2号方于双侧气瘿穴；对照组40例内服左甲状腺素片。观察两组患者治疗后的效果、治疗前后甲状腺激素[促甲状腺激素（TSH）、血清游离三碘甲腺原氨酸（FT3）、血清游离甲状腺素（FT4）]水平、甲状腺结节大小的变化及结节内血流成像变化。 结果 治疗组总有效率为92.5%，对照组总有效率为47.5%，两组比较差异有统计学意义（P 0.05），对照组治疗后TSH[（0.73±0.34）mU/L]水平与治疗前[（1.96±0.79）mU/L]比较明显下降（P 0.05），FT3[（3.95±2.33）pmol/L]、FT4[（13.95±2.61）pmol/L]水平与治疗前[FT3：（3.52±1.06）pmol/L；FT4：（13.49±3.65）pmol/L]比较明显增高（P 0.05）。两组治疗后结节内血流分级比较，差异有统计学意义（P 0.05）。 结论 中药内服结合外敷气瘿穴治疗甲状腺良性结节效果较好，值得临床推广运用。 　　[关键词] 中药内服；气瘿穴；甲状腺良性结节 　　[中图分类号] R581 [文献标识码] A [文章编号] 1673-7210（2016）01（c）-0150-04 　　Clinical study of oral medicinal herbs combined with external application of qi goiter acupoint in the treatment of benign thyroid nodules 　　LIU Hongfang DIAO Weiqiang HU Xuhui ZHAO Jincheng CHEN Hao HUANG Yunshan ZENG Jianqiu CHEN Yuechao 　　Department of General Surgery， Zengcheng Hospital of Traditional Chinese Medicine in Guangzhou City， Guangdong Province， Guangzhou 511300， China 　　[Abstract] Objective To observe the clinical effect of oral Sanjie Ⅰ Prescription combined with local application of qi goiter acupoint in the treatment of benign thyroid nodules. Methods Eighty patients with benign thyroid nodules admitted to Zengcheng Hospital of Traditional Chinese Medicine in Guangzhou City from July 2014 to July 2015 were selected and randomly divided into two groups. 40 cases of the treatment group were taken oral Chinese medicine Sanjie Ⅰ Prescription combined with local application of Sanjie Ⅱ Prescription on bilateral qi goiter acupoint； 40 cases of the control group were taken oral Levothyroxine Tablets. The effects of two groups after treatment， the levels of thyroid hormones [thyroid stimulating hormone （TSH）， serum free three iodine thyroid gland （FT3） and serum free thyroid hormone （FT4）] before and after treatment， the changes of the size of thyroid nodules and the changes of blood flow imaging in the