亚低温治疗急性重型颅脑损伤疗效及对预后影响.docVIP

亚低温治疗急性重型颅脑损伤的疗效及对预后的影响 　　[摘要] 目的：观察亚低温治疗急性重型颅脑损伤的疗效及对预后的影响。方法：将本院2007年1月～2010年1月收治的80例重症颅脑损伤患者根据治疗方法随机分为观察组和对照组各40例，两组均予抗感染、止血、降颅压、纠酸等治疗，其中观察组在上述常规治疗的基础上给予亚低温治疗，比较两组的手术疗效及对患者预后的影响。结果：治疗后观察组患者预后的良好率明显高于对照组。观察组并发症发生率低于对照组，差异有统计学意义（P0.05）。结论：在常规治疗的基础上同时应用亚低温治疗急性重型颅脑损伤疗效确切，可以明显改善患者的预后，降低并发症的发生率。 　　[关键词] 亚低温；急性重症颅脑损伤；预后；疗效 　　[中图分类号] R651.1+5 [文献标识码]A[文章编号]1674-4721（2011）03（c）-015-02 　　 　　Hypothermia treatment of acute severe head injury on the prognosis of the efficacy 　　WANG Kai, XIAO Yuqiang, FU Liqi, WANG Xiaomin, WANG Yuchun 　　Department of Neurosurgery, Daqing Oilfield General Hospital in Heilongjiang Province, Daqing 163001, China 　　[Abstract] Objective: To observe the hypothermia treatment of acute severe brain injury and the effect on prognosis. Methods: The hospital in January 2007 to 2010 admitted on Jan. 80 patients with severe traumatic brain injury patients according to treatment conditions randomly divided into two groups and control group 40 patients, two groups herein were anti-inflammatory, hemostatic, reducing cranial pressure, correcting acid treatment, the treatment group on the basis of the conventional treatment for mild hypothermia therapy, surgical treatment groups were compared and the impact on prognosis. Results: The observation group were significantly higher in the good prognosis. Complication rate in observation group than control group, significant difference (P0.05). Conclusion: Based on the conventional treatment while the treatment of mild hypothermia is effective in acute severe brain injury, can significantly improve prognosis and reduce the incidence of complications. 　　[Key words] Hypothermia; Acute severe traumatic brain injury; Prognosis; Effect 　　 　　近年来，交通事故伤、坠落伤及其他类型的各种创伤致急性重型颅脑损伤的发生率仍较高，急性重型颅脑损伤仍是神经外科的常见病、多发病。由于脑组织的直接受损及颅内高压、缺血缺氧、各种炎症介质、再灌注损伤等多种因素的作用，严重影响患者的治疗及预后。目前临床较多文献报道，亚低温治疗可以明显促进脑功能的修复，对颅脑损伤患者有肯定的疗效[1]。本研究旨在观察亚低温治疗急性重型颅脑损伤的疗效及对预后的影响。 　　1 资料与方法 　　1.1 一般资料 　　入选的80例病例资料均为本院2007年1月～2010年1月住院治疗患者，所有患者均行头颅CT检查确诊。