亚临床甲状腺功能减退对冠状动脉粥样硬化患者影响.docVIP

亚临床甲状腺功能减退对冠状动脉粥样硬化患者的影响 　　【摘要】 目的：研究亚临床甲状腺功能减退对冠状动脉粥样硬化患者的影响。方法：采用随机数字表法将冠状动脉粥样硬化患者分为两组，对照组为甲状腺功能未减退的冠状动脉粥样硬化患者，实验组为甲状腺功能减退的冠状动脉粥样硬化的患者，对比两组患者的血脂各项指标，以及两组患者的冠状动脉粥样硬化的程度对比。结果：与对照组患者比较，实验组患者的血清中促甲状腺激素、甘油三酯、低密度脂蛋白胆固醇以及总胆固醇均升高，高密度脂蛋白胆固醇明显降低，差异具有统计学意义（P0.05）；实验组患者冠状动脉粥样硬化率较对照组高，差异具有统计学意义（P0.05）。结论：亚临床甲状腺功能减退对冠状动脉粥样硬化有一定的潜在危险因素，值得引起重视并积极进行预防和改善。 　　【关键词】 亚临床甲状腺功能减退； 动脉粥样硬化； 血脂； 冠状动脉疾病 　　Subclinical Hypothyroidism’s Influence on Coronary Artery Atherosclerosis Patients/SU Li-jun， LIU Yu-fa， CHEN Guang-xin.//Medical Innovation of China，2015，12（10）：136-138 　　【Abstract】 Objective：To study Subclinical hypothyroidism’s influence on coronary artery atherosclerosis patients.Method：These coronary artery atherosclerosis patients were divided into control group and experimental group according to random number table， these coronary artery atherosclerosis patients whose thyroid function did not decline belonged to control group， while these coronary artery atherosclerosis patients whose thyroid function declined belonged to experimental group， compared two group’s blood fat situations and their coronary artery atherosclerosis conditions.Result：Compared with the control group， the experimental group’s thyrotropic hormone， triglyceride， low density lipoprotein-cholesterol and cholesterol in blood serum raised a lot， high density lipoprotein-cholesterol significantly decreased （P0.05）， it had statistics meaning.Experimental group’s coronary artery atherosclerosis ratio was higher than control group’s （P0.05）， it had statistics meaning.Conclusion：Subclinical hypothyroidism is one of the potential risk factors for coronary artery atherosclerosis patients， it is worthy of our attention and should prevent and improve it positively. 　　【Key words】 Subclinical hypothyroidism； Artery atherosclerosis； Blood fat； Coronary artery disease 　　First-author’s address：Zibo Central Hospital， Zibo 255036， China 　　doi：10.3969/j.issn.1674-4985.2015.10.044 　　亚临床甲状腺功能减退，是指患者的正常甲状腺激素分泌不足，或是甲状腺释放以及合成障碍