保留盆腔神经广泛子宫切除术治疗宫颈癌效果及其对卵巢功能影响.docVIP

保留盆腔神经的广泛子宫切除术治疗宫颈癌的效果及其对卵巢功能的影响 　　【摘要】 目的：探?保留盆腔神经的广泛子宫切除术治疗宫颈癌的效果及其对卵巢功能的影响。方法：选取2014年1月-2016年6月于本院接受治疗的宫颈癌患者85例为研究对象，按病情分为对照组（43例）和观察组（42例）。对照组患者行常规子宫切除术+盆腔淋巴结清扫术，观察组患者行保留盆腔神经的广泛子宫切除术+盆腔淋巴结清扫术。比较两组患者的治疗效果及术后卵巢功能情况。结果：两组的手术时间、术中出血量比较，差异均无统计学意义（P0.05）。观察组患者术后残余尿50 mL、术后残余尿100 mL及术后排气和排便时间均明显短于对照组，差异均有统计学意义（P0.05）。两组患者术后膀胱灌注阶段首次排尿感和急迫排尿感均增大，排尿阶段的最大膀胱压、最大尿流率及最大逼尿肌压均减少，最大腹压则增大，且对照组患者上述指标变化幅度更大，差异均有统计学意义（P0.05）。观察组术后血清E2含量明显高于对照组，而血清LH含量、FSH含量均显著低于对照组，差异均有统计学意义（P0.05）。结论：保留盆腔神经的广泛子宫切除术能更好地改善宫颈癌患者疗效并保留卵巢功能，值得临床推广应用。 　　【关键词】 宫颈癌； 广泛子宫切除术； 卵巢功能 　　Effect of Extensive Hysterectomy with Pelvic Nerve Preservation on Cervical Cancer and Its Effect on Ovarian Function/LAI Xiao-qing.//Medical Innovation of China，2017，14（09）：052-055 　　【Abstract】 Objective：To investigate the effect of extensive pelvic hysterectomy for the treatment of cervical cancer and its effect on ovarian function.Method：85 patients with cervical cancer in our hospital from January 2014 to June 2016 were selected as the research objects，they were divided into observation group （42 cases） and control group （43 cases）.Patients in control group were adopted the surgery of conventional hysterectomy and pelvic lymph node dissection，while the patients in observation group underwent extensive hysterectomy with pelvic nerve preservation and pelvic lymph node dissection.The clinical effect and ovary function were compared between the two groups.Result：There were no significant differences in operation time and blood loss between the two groups（P0.05）.The residual urine was less than 50 mL，the residual urine was less than 100 mL，and the postoperative exhaust and defecation time of observation group were significantly shorter than those in control group，the differences were statistically significant（P 　　【Key words】 Cervical cancer； Extensive hysterectomy； Ovary function 　　First-author’s address：The Sixth People’s Hospital of Shenzhen，Shenzhen 518101，China 　　doi：10.3969/j.issn.1674-4985.2017.09.015 　　宫颈癌是临床妇科常见的恶