化疗DC―CIK方案治疗非小细胞肺癌临床效果.docVIP

化疗DC―CIK方案治疗非小细胞肺癌临床效果 　　[摘要]目的 分析非小?胞肺癌患者采用常规化疗与DC-CIK细胞联合治疗的临床效果。方法 选择我院2014年11月～2016年11月收治的82例非小细胞肺癌患者，随机分为对照组和治疗组，各41例。对照组采用常规化疗方案进行治疗，治疗组采用常规化疗与DC-CIK细胞联合进行治疗，比较两组的治疗效果。结果 治疗组治疗后的细胞因子相关指标水平恢复正常时间短于对照组，差异有统计学意义（P0.05）；治疗组仅有17例不良反应出现，少于对照组的35例，差异有统计学意义（P0.05）。治疗组的总有效率为87.8%，高于对照组的65.9%，差异有统计学意义（P0.05）。两组治疗后的T淋巴细胞亚群含量水平改善幅度优于治疗前，治疗组治疗后的T淋巴细胞亚群含量水平改善幅度优于对照组，差异有统计学意义（P0.05）。结论 非小细胞肺癌患者采用常规化疗联合与DC-CIK细胞进行治疗可以有效改善细胞因子含量，提高治疗有效率，减少化疗不良反应，缩短治疗时间。 　　[关键词]非小细胞肺癌；常规化疗；DC-CIK细胞；效果 　　[中图分类号] R734.2 [文献标识码] A [文章编号] 1674-4721（2017）09（b）-0051-03 　　Clinical effects of general chemotherapy combined with DC-CIK cell in the treatment of non small cell lung cancer 　　TAO Li-ming LE Wei WANG Fan WAN Bao-lin 　　Department of Internal Medicine-Oncology，the Third People′s Hospital of Jiujiang City in Jiangxi Province，Jiujiang 332000，China 　　[Abstract]Objective To analyze the clinical effects of general chemotherapy combined with DC-CIK cell in the treatment of non small cell lung cancer.Methods 82 patients with non small cell lung cancer who treated in our hospital from November 2014 to November 2016 were selected and randomly divided into the control group and the treatment group，each group was 41 cases.The control group was used general chemotherapy and the treatment group was used general chemotherapy combined with DC-CIK cell.The therapeutic effects of the two groups was compared.Results The time of the level of cytokine related indicators returned to normal in the treatment group was shorter than that in the control group，with significant difference （P0.05）.There were only 17 cases of adverse reactions in the treatment group，and 35 cases in the control group，the difference between the two groups was significant （P0.05）.The total effective rate of the treatment group was 87.8%，which was higher than 65.9% in the control group，with significant difference （P0.05）.The improvement of T lymphocyte subsets content in the two groups after treatment was significantly better than that