动态检测PCT与hs―CRP在全身和局部细菌感染性疾病诊断中临床研究.docVIP

动态检测PCT与hs―CRP在全身和局部细菌感染性疾病诊断中临床研究 　　【摘要】 目的：研究与观察动态检测PCT与hs-CRP在全身和局部细菌感染性疾病诊断中的临床作用。方法：选取2015年6月-2016年11月本院的诊治的56例全身细菌感染患者为A组，56例局部细菌感染者为B组，56名健康者为C组，比较A、B组治疗前和治疗后12 h、1 d、3 d、5 d及7 d时和C组的血清PCT与hs-CRP水平与阳性率。结果：A组、B组治疗前和治疗后12 h、1 d、3 d、5 d及7 d的血清PCT与hs-CRP水平与阳性率均高于C组，且A组的血清PCT与hs-CRP水平与阳性率均高于B组，A组与B组治疗后的血清PCT与hs-CRP水平与阳性率均持续降低，治疗后1、3、5及7 d的血清水平与阳性率均低于治疗前和治疗后12 h，差异均有统计学意义（P0.05）。结论：PCT与hs-CRP在全身和局部细菌感染性疾病的诊断与区别中具有较高的价值，且其动态变化对于疾病的发展转归与治疗指导有积极的临床意义。 　　【关键词】 动态检测； PCT； hs-CRP； 全身细菌感染； 局部细菌感染 　　【Abstract】 Objective：To study and observe the clinical role of PCT and hs-CRP dynamic detection in the diagnosis of systemic and local bacterial infectious diseases.Method：From June 2015 to November 2016，56 patients with systemic bacterial infection in our hospital were selected as the group A，56 patients with local bacterial infection were selected as the group B，56 healthy persons were selected as group C，then the serum PCT and hs-CRP levels and positive rates of group A and group B before the treatment and at 12 hours，1st，3rd，5th and 7th day after the treatment and group C were compared.Result：The serum PCT and hs-CRP levels and positive rates of group A and group B before the treatment and at 12 hours，1st，3rd，5th and 7th day after the treatment were all higher than those of group C，the serum PCT and hs-CRP levels and positive rates of group A were all higher than those of group B，the serum PCT and hs-CRP levels and positive rates of group A and group B all continuously decreased，and the serum levels and positive rates at 1st，3rd，5th and 7th day after the treatment were all lower than those before the treatment and at 12 hours after the treatment，the differences were statistically significant（P0.05）.Conclusion： Dynamic detection of PCT and hs-CRP has high value in diagnosis and differentiation of systemic and local bacterial infectious diseases，which also has positive clinical significance for guide disease development and treatment. 　　【Key words】 Dynamic detection； PCT