右美托咪定联合地佐辛对腰麻剖宫产术中牵拉反应影响.docVIP

右美托咪定联合地佐辛对腰麻剖宫产术中牵拉反应影响 　　【摘要】 目的：观察右美托咪定联合地佐辛在对腰麻剖宫产术中牵拉反应的影响。方法：选择2016年1-8月在本院行腰麻剖宫产的产妇80例，采用随机数字法分为右美托咪定+芬太尼组（对照组）和右美托咪定+地佐辛组（观察组），每组各40例。断脐后，两组产妇10 min内均静脉泵入右美托咪定0.6 μg/kg，对照组产妇静脉注射芬太尼0.05 mg，观察组产妇静脉注射地佐辛5 mg。比较两组产妇给药前、给药后10 min、探查时和术毕的SBP、DBP、HR、Ramsay评分以及牵拉反应情况。结果：两组产妇腰麻后，血压和心率较入室时均有下降（P0.05）；观察组在探查时的SBP和DBP低于对照组（P0.05）。两组产妇在探查时的Ramsay评分较入室时均下降（P0.01），观察组探查时Ramsay评分高于对照组（P0.01）。与对照组比较，观察组术中牵拉反应较轻（P0.01）。结论：地佐辛用于剖宫产术中抑制牵拉反应效果优于芬太尼。 　　【关键词】 右美托咪定； 地佐辛； 芬太尼； 剖宫产； 牵拉反应 　　【Abstract】 Objective：To evaluate the effect of dexmedetomidine Combined with dezocine on traction reactions of spinal anesthesia in cesarean section.Method：80 cases of cesarean section undergoing lumbar anesthesia in our hospital from January to August 2016 were selected，according to the random number table method，they were randomly divided into Dexmedetomidine + Fentanyl group（control group） and Dexmedetomidine + Dezocine group（observation group），40 cases in each group.After cutting the umbilical cord，two groups were intravenous infusion of dexmedetomidine given 0.6 μg/kg within 10 min，control group was intravenous Fentanyl 0.05 mg，observation group received intravenous injection of Dezocine 5 mg.SBP，DBP，HR，Ramsay score and traction reactions were compared before the drug administration，10 min，abdominal exploration and the end of surgery.Result：Two groups had lower blood pressure and heart rate when they were pregnant（P0.05）；the SBP and DBP in observation group was less than that in control group when abdominal exploration（P0.05）.The ramsay score in two groups were decreased at the time of abdominal exploration compared with burglary（P0.01），at the time of abdominal exploration，the ramsay score in observation group was higher than that in control group（P0.01）.Compared with control group，the degree of intraoperative traction reactions in observation group was lessened（P0.01）.Conclusion：Dezocine was better than Fentanyl on the traction reaction inhibition of cesarean section. 　　【Key words】 Dex