右美托咪定联合舒芬太尼在全身麻醉患者术后镇痛中应用效果.docVIP

右美托咪定联合舒芬太尼在全身麻醉患者术后镇痛中应用效果 　　[摘要]目的 对右美托咪定联合舒芬太尼在全麻患者术后镇痛中的应用效果进行观察。方法 选取2016年9月～2017年8月我院收治的104例全麻手术患者作为研究对象，按照随机数字表法将其分为研究组和对比组，每组各52例。对比组患者使用舒芬太尼进行镇痛，研究组患者使用右美托咪定联合舒芬太尼进行镇痛。对比分析两组患者的Ramsay镇静评分、VAS评分、切口疼痛面积及不良反应发生率。结果 两组患者各时间段的Ramsay镇静评分比较，差异无统计学意义（P0.05）。术后30 min、3 h、48 h，研究组患者的VAS评分均低于对比组，差异有统计学意义（P0.05）。结论 全麻患者术后镇痛中使用右美托咪定联合舒芬太尼的效果更好，起到有效减轻疼痛评分、较小切口疼痛面积效果，应在临床实践中予以广泛推广并使用。 　　[关键词]右美托咪定；舒芬太尼；全麻患者；术后镇痛 　　[中图分类号] R614.2 [文献标识码] A [文章编号] 1674-4721（2018）2（c）-0068-03 　　[Abstract]Objective To observe the application effect of Dexmedetomidine combined with Sufentanil for postoperative analgesia in general anesthesia patients.Methods A total of 104 patients undergoing general anesthesia in our hospital from September 2016 to August 2017 were selected as subjects.According to a random number table method，they were divided into study group and control group，52 cases in each group.In the control group，Sufentanil was used for analgesia，while in the study group，Dexmedetomidine combined with Sufentanil for analgesia was adopted.The Ramsay sedation score，visual analogue scale （VAS） score，incision pain area and incidence of adverse reactions were compared and analyzed in the two groups.Results There was no statistically significant difference in Ramsay sedation score between the two groups （P0.05）.After 30 min，3 h and 48 h，the VAS score of the study group was lower than that of the control group，and the differences were statistically significant （P0.05）.Conclusion The effect of Dexmedetomidine combined with Sufentanil for postoperative analgesia in general anesthesia patient is better compared with sole Sufentanil，which can effectively relieve pain and reduce the area of incision pain，and should be widely used and promoted in clinical practice. 　　[Key words]Dexmedetomidine；Sufentanil；General anesthesia patients；Postoperative analgesia 　　?g后疼痛是影响手术效果、加重患者心理负担的关键因素之一，严重时甚至会引发患者心脑血管疾病或肺部并发症，不仅危害患者健康和生命安全，也在一定程度上加重了患者及家庭的经济负担，而减轻术后疼痛对于患者内分泌功能、代谢紊乱的恢复起到重要影响[1-2]，有利于病症的恢复，因此，