妊娠晚期B族链球菌带菌者预防性治疗临床研究.docVIP

妊娠晚期B族链球菌带菌者预防性治疗临床研究 　　[摘要] 目的 研究并探?妊娠晚期B族链球菌带菌者实施预防性治疗的临床效果。方法 该研究病例观察时间段为2016年1―6月，方便收集该院妇产科在该时间段内定期产检及分娩的孕妇共计90例作为研究对象。所有患者均明确诊断为B族链球菌带菌者。根据治疗情况进行分组，将接受预防性治疗的60例患者作为观察组，组内根据预防性治疗时机的不同分为观察A组（n=30例）以及观察B组（n=30例），另将未接受预防性治疗的30例患者作为对照组。对比观察各组患者在母婴妊娠结局方面的差异。结果 对比各组母婴妊娠结局中不良事件发生率，对照组胎膜早破、早产、宫内感染、新生儿感染、以及产褥感染事件发生率分别为20.00%（6/30）、16.67%（5/30）、16.67%（5/30）、16.67%（5/30）、以及13.33%（4/30），均显著高于观察A组、观察B组，差异有统计学意义（P0.05）。结论 针对妊娠晚期B族链球菌带菌者药物敏感情况，选用敏感抗生素药物进行预防性治疗对改善母婴妊娠结局有积极效果，预防性治疗最佳时机为临产或胎膜早破时。 　　[关键词] 妊娠晚期；B族链球菌；预防性治疗 　　[中图分类号] R714 [文献标识码] A [文章编号] 1674-0742（2017）09（c）-0104-03 　　Clinical Research on Preventive Treatment of Group b Streptococcus Carriers in the Late Pregnancy 　　JIN Hong 　　Second Department of Clinical Laboratory， Laiwu Central Hospital of Xinwen Mining Group of Laiwu， Laiwu， Shandong Province， 271103 China 　　[Abstract] Objective To research and study the clinical effect of preventive treatment of group b streptococcus carriers in the late pregnancy. Methods 90 cases of pregnant women with regular antenatal care and delivery from January to June 2016 were convenient selected and all patients were definitely diagnosed with group b streptococcus carriers， and the patients were divided into the observation group with preventive treatment and the control group without preventive treatment with 60 cases in each， the observation group were divided into two groups with 30 cases in each， respectively the observation A group and observation B group， and the difference in the maternal and child pregnant outcome of each group was compared. Results The incidence rates of adverse events of maternal and pregnant outcomes such as premature rupture of membranes， premature delivery， intrauterine infection， neonatal infection， and puerperal infection events were respectively 20.00%（6/30）， 16.67%（5/30）， 16.67%（5/30）， 16.67%（5/30）， and 13.33%（4/30）， which were obviously higher than those in the observation A group and in the observation B group， and the test（P0.05）， and th