洗必泰敷料治疗在PICC局部感染护理中效果研究.docVIP

洗必泰敷料治疗在PICC局部感染护理中效果研究 　　[摘要] 目的 探?洗必泰敷料治疗在经外周静脉置入中心静脉导管（peripherally inserted central catheter，PICC）局部感染护理中的效果。 方法 选取2013年12月～2015年12月期间在我院确诊治疗的PICC相关性局部感染患者100例，依据随机数表法随机分为洗必泰组和碘伏组，每组50例，碘伏组患者给予碘伏湿敷换药治疗，洗必泰组患者给予洗必泰敷料换药治疗，采用酶联免疫吸附法（enzyme-linked immunosorbent，ELISA）检测血清降钙素原（proclacitonin，PCT）、C反应蛋白（c-reactive protein，CRP）水平，统计分析所有患者治疗疗效、换药次数、导管留置和治愈时间及治疗前后血清PCT、CRP、白细胞计数（white blood cell count，WBC）水平。 结果 洗必泰组患者治疗有效率明显高于碘伏组，差异有统计学意义（P0.05）；洗必泰组患者换药次数和治愈时间明显短于碘伏组，前者导管留置时间明显长于后者，差异有统计学意义（P0.05）；洗必泰组患者治疗后血清PCT、CRP、WBC水平明显低于碘伏组，差异有统计学意义（P0.05）。 结论 洗必泰敷料治疗可有效提高PICC相关性局部感染患者的治疗疗效，能够有效改善机体的炎症状态和减少换药次数，且可有效延长导管留置时间，值得临床作进一步推广。 　　[关键词] 洗必泰敷料；经外周静脉置入中心静脉导管；局部感染；导管留置时间 　　[中图分类号] R473.73 [文献标识码] B [文章编号] 1673-9701（2016）34-0153-04 　　Study on the effect of chlorhexidine dressing in PICC local infection nursing 　　YU Suqin GUO Haizhen 　　Department of General Oncology， Hangzhou Cancer Hospital， Hangzhou 310002， China 　　[Abstract] Objective To investigate the effect of chlorhexidine dressing on local infection nursing by peripherally inserted central catheters（PICC）. Methods 100 patients with PICC in our hospital from December 2013 to December 2015 were selected. According to the random number table method， they were randomly divided into chlorhexidine group and iodophor group， with 50 patients in each group. The patients in the iodophor group were given iodophor wet dressing treatment， and the patients in the chlorhexidine group were given chlorhexidine dressing treatment. The levels of serum procalcitonin（PCT） and c-reactive protein（CRP） were detected by enzyme-linked immunosorbent assay （ELISA）， and the curative effects， number of dressing， catheter retention time and healing time， and the levels of serum PCT， CRP and white blood cell count（WBC） before and after the treatment were statistically analyzed. Results The effective rate of treatment in the chlorhexidine group was significantly higher than that in the iodophor group， and the difference was statistically signific