慢性膝关节疼痛针刺治疗定量差异再分析.docVIP

慢性膝关节疼痛针刺治疗定量差异再分析 　　摘 要：引入定量差异（QD）对Hinman等发现毫针或激光针刺治疗50岁以上患者的慢性膝关节疼痛的效果并不优于激光假照射组的原始数据进行了再分析。在Hinman等的9个评价指标的基础上，定义了9个过程参数和33个组合参数的过程参数分第12周和1年两个时间段，总共获得102个表型参数。研究发现，毫针组、激光组和激光假照射组优于对照组的统计差异或QD分别有64、22和39个表型参数达到显著性量级；毫针组优于激光组和激光假照射组的QD分别有29和10个表型参数达到显著性量级；激光假照射组优于激光组的QD有11个。结果表明，毫针、激光假照射和激光对50岁以上膝关节疼痛患者的治疗效果由高到低依次优于对照组。 　　关 键 词：运动医学；骨关节炎；慢性膝关节疼痛；针刺；激光；表型组学；定量差异 　　中图分类号：G804.5 文献标志码：A 文章编号：1006-7116（2017）02-0115-07 　　A reanalysis of quantitative differences in the acupuncture therapy of 　　chronic knee joint pain 　　WU Chong-yun，YANG Luo-dan，LIU Cheng-yi，ZHU Ling，DUAN Rui，ZHANG Quan-guang 　　（Laboratory of Laser Sports Medicine，School of Physical Education，South China Normal University， 　　Guangzhou 510006，China） 　　Abstract： By introducing quantitative difference （QD）， the authors reanalyzed the original data which showed that the effect of needle or laser acupuncture therapy on chronic knee joint pain suffered by patients over 50 was not better than that on the laser sham irradiation group， found by Hinman etc. Based on the 9 evaluation indexes set by Hinman， the authors defined 9 process parameters and 33 process parameters of composite parameters， and obtained totally 102 phenotypic parameters in such two time periods as 12 weeks and 1 year， and revealed the following findings： among the statistical differences or QD which showed that the effect of the needle group， the laser group and the laser sham irradiation group was better than that of the control group， there were respectively 64， 22 and 39 phenotypic parameters which reached a significant level； among the QD which showed that the effect of the needle group was better than that of the laser sham irradiation group， there were respectively 29 and 10 phenotypic parameters which reached a significant level； there were 11 QD which showed that the effect of the laser sham irradiation group was better than that of the laser group. The said findings indicated that the therapeutic effect of needle， laser sha