恩替卡韦配合治疗慢性乙型肝炎后肝硬化临床价值研究.docVIP

恩替卡韦配合治疗慢性乙型肝炎后肝硬化临床价值研究 　　[摘要] 目的 探析恩替卡韦配合治疗慢性乙型肝炎后肝硬化患者的临床效果。 方法 随机抽选2011年5月～2014年5月在本院进行治疗的慢性乙型肝炎肝硬化患者70例，按照抽签法将其平均分成对照组和观察组。对照组患者给予常规方法治疗，观察组在常规方法治疗基础上给予恩替卡韦治疗，观察比较两组患者的治疗情况及临床效果。 结果 经过治疗，观察组患者的ALT、AST、TBiL指标水平较治疗前有显著改善，且明显优于对照组患者，其治疗总有效率（92.68%）高于对照组患者（70.73%），差异有统计学意义（P0.05）。 结论 恩替卡韦治疗慢性乙型肝炎后肝硬化患者，临床疗效显著，患者肝功能改善良好，是一种理想、有效、科学的临床治疗方法。 　　[关键词] 慢性乙型肝炎后肝硬化；恩替卡韦；临床效果 　　[中图分类号] R512.6+2 [文献标识码] A [文章编号] 1674-4721（2015）07（c）-0086-03 　　Study on the clinical value of entecavir in the treatment of liver cirrhosis after chronic hepatitis B 　　HUANG Rong-rong 　　Department of Gastroenterology，People′s Hospital in Qidong City of Jiangsu Province，Qidong 226200，China 　　[Abstract] Objective To explore and analyze the clinical conditions and effects of entecavir in the treatment of liver cirrhosis after chronic hepatitis B. Methods 70 patients with chronic hepatitis B and liver cirrhosis who were treated in our hospital from May 2011 to May 2014 were randomly selected.They were evenly assigned to control group and observation group according to the method of lots drawing，with 35 patients in each group.The control group was given clinical treatment and diagnosis with regular method，and observation group was given clinical treatment and diagnosis with entecavir.Conditions of treatment and diagnosis and clinical effects between two groups of patients were analyzed statistically and compared. Results According to the statistical analysis，levels of ALT， AST and TBiL in observation group after the treatment was significantly improved respectively compared to that before the treatment，and were also better than that of control group.Its total effective rate of treatment （92.68%） was significantly higher than 70.73% in control group.The differences of results compared between two groups were substantial，with statistical difference（P0.05）. Conclusion Entecavir applied in the treatment and diagnosis of patients with liver cirrhosis after chronic hepatitis B has significantly clinic